小儿直肠脱垂--内科和外科治疗回顾。

IF 3.8 Q2 GASTROENTEROLOGY & HEPATOLOGY Translational gastroenterology and hepatology Pub Date : 2024-06-12 eCollection Date: 2024-01-01 DOI:10.21037/tgh-23-128
Karishma Kodia, Carlos Theodore Huerta, Eduardo A Perez
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引用次数: 0

摘要

背景和目的:直肠脱垂是一种常见的肛门直肠疾病,虽然在成年人群中更为多见,但也可能发生在儿童和青少年身上。虽然许多病例无需干预即可自愈,但较新的微创手术的出现为儿童患者提供了选择。在此,我们回顾了过去几十年来儿科直肠脱垂的病理生理学、病因学、表现、诊断和处理原则:从美国国家卫生研究院国家医学图书馆 MEDLINE 和 PubMed 等向公众开放的免费数据库中查询 1975 年 1 月 1 日至 2023 年 12 月 1 日期间发表的文献。没有附带英文翻译或完全用外语撰写的稿件被排除在外:导致儿童直肠脱垂的病因有很多,包括便秘、胃肠道感染性和非感染性病因、囊性纤维化、营养不良、神经源性、解剖性、铅点和虐待。直肠脱垂的初始治疗方法是药物治疗,解决与直肠脱垂相关的潜在疾病,同时尝试人工缩肛。对于复发性直肠脱垂的患者,除了采用开放式和较新的微创方法进行手术直肠切除术外,还可选择各种非侵入性和程序性治疗方法,包括注射硬化剂疗法和肛门环切术:尽管在过去的几十年里,儿科肛门直肠疾病的评估、手术治疗和外科治疗取得了重大进展,但临床医生和外科医生在治疗儿童和青少年直肠脱垂方面的做法仍存在很大差异。为了改善这一患者群体的临床治疗效果,未来仍有许多问题需要研究。
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Rectal prolapse in the pediatric population-a narrative review of medical and surgical management.

Background and objective: Although more frequent in the adult population, rectal prolapse is a common anorectal condition that can occur in children and adolescents. While many cases spontaneously resolve without the need for intervention, the advent of newer minimally invasive procedures and operations have provided options for pediatric patients. Here, we review the pathophysiology, etiology, presentation, diagnosis and principles of management of rectal prolapse in the pediatric population as it has evolved over the past several decades.

Methods: The literature was queried from free databases available to the public including the National Institute of Health National Library of Medicine MEDLINE and PubMed for manuscripts published from January 1, 1975 to December 1, 2023. Manuscripts without an accompanying English translation or those written entirely in foreign languages were excluded.

Key content and findings: Numerous conditions contribute to rectal prolapse in children, including constipation, gastrointestinal infectious and non-infectious etiologies, cystic fibrosis, malnutrition, neurogenic, anatomic, lead points, and abuse. Initial management of rectal prolapse is medical management, addressing the underlying condition associated with rectal prolapse along with attempted manual reduction. For patients with recurrent rectal prolapse, a variety of noninvasive and procedural management options are available including injection sclerotherapy and anal encirclement in addition to surgical rectopexy by open and newer minimally invasive methods.

Conclusions: Despite significant advances in the evaluation, procedural and surgical management of pediatric anorectal conditions in the last few decades, there continues to be substantial variation in clinicians' and surgeons' practice for the treatment of rectal prolapse in children and adolescents. Much remains to be studied in the future to improve clinical outcomes for this patient population.

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