昼夜节律综合征中的肠道微生物群和饮食行为。

IF 11.4 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM Trends in Endocrinology and Metabolism Pub Date : 2024-08-01 DOI:10.1016/j.tem.2024.07.008
Jorge R Soliz-Rueda, Cristina Cuesta-Marti, Siobhain M O'Mahony, Gerard Clarke, Harriët Schellekens, Begoña Muguerza
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引用次数: 0

摘要

进食行为与昼夜节律密切相关。摄入食物的种类、时间和数量以及宿主的昼夜节律直接影响肠道微生物群,而肠道微生物群反过来又影响宿主的昼夜节律,并调节食物摄入量,使其超出平衡饮食的范围。本观点讨论了肥胖环境引起的食物摄入量和昼夜节律紊乱对肠道-大脑轴信号传导的影响。我们还探讨了肠道微生物群改变对食物摄入行为和昼夜节律性影响的潜在机制。了解肠道微生物群、昼夜节律和不健康饮食行为之间的相互影响对于解决肥胖问题至关重要,而肥胖仍是当代最大的社会挑战之一。
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Gut microbiota and eating behaviour in circadian syndrome.

Eating behaviour and circadian rhythms are closely related. The type, timing, and quantity of food consumed, and host circadian rhythms, directly influence the intestinal microbiota, which in turn impacts host circadian rhythms and regulates food intake beyond homeostatic eating. This Opinion discusses the impact of food intake and circadian disruptions induced by an obesogenic environment on gut-brain axis signalling. We also explore potential mechanisms underlying the effects of altered gut microbiota on food intake behaviour and circadian rhythmicity. Understanding the crosstalk between gut microbiota, circadian rhythms, and unhealthy eating behaviour is crucial to addressing the obesity epidemic, which remains one of the biggest societal challenges of our time.

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来源期刊
Trends in Endocrinology and Metabolism
Trends in Endocrinology and Metabolism 医学-内分泌学与代谢
CiteScore
20.10
自引率
0.00%
发文量
98
审稿时长
82 days
期刊介绍: Trends in Endocrinology and Metabolism (TEM) stands as a premier Reviews journal in the realms of metabolism and endocrinology. Our commitment is reflected in the publication of refined, concise, and highly impactful articles that delve into cutting-edge topics, encompassing basic, translational, and clinical aspects. From state-of-the-art treatments for endocrine diseases to groundbreaking developments in molecular biology, TEM provides comprehensive coverage. Explore recent advancements in diabetes, endocrine diseases, obesity, neuroendocrinology, immunometabolism, molecular and cellular biology, and a myriad of other areas through our journal. TEM serves as an invaluable resource for researchers, clinicians, lecturers, teachers, and students. Each monthly issue is anchored by Reviews and Opinion articles, with Reviews meticulously chronicling recent and significant developments, often contributed by leading researchers in specific fields. Opinion articles foster debate and hypotheses. Our shorter pieces include Science & Society, shedding light on issues at the intersection of science, society, and policy; Spotlights, which focus on exciting recent developments in the literature, and single-point hypotheses as Forum articles. We wholeheartedly welcome and encourage responses to previously published TEM content in the form of Letters.
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