{"title":"用于治疗勃起功能障碍和其他疾病的传统和试验性磷酸二酯酶 5 抑制剂概述","authors":"Ezzat A. Ismail, Ahmed I. El-Sakka","doi":"10.1080/13543784.2024.2388569","DOIUrl":null,"url":null,"abstract":"There is a rising concern about developing innovative, efficacious PDE5I molecules that provide better safety, efficacy and tolerability with less adverse effects. Innovative PDE5I with dual target...","PeriodicalId":12313,"journal":{"name":"Expert opinion on investigational drugs","volume":"80 1","pages":""},"PeriodicalIF":4.9000,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An overview of conventional and investigational phosphodiesterase 5 inhibitors for treating erectile dysfunction and other conditions\",\"authors\":\"Ezzat A. Ismail, Ahmed I. El-Sakka\",\"doi\":\"10.1080/13543784.2024.2388569\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"There is a rising concern about developing innovative, efficacious PDE5I molecules that provide better safety, efficacy and tolerability with less adverse effects. Innovative PDE5I with dual target...\",\"PeriodicalId\":12313,\"journal\":{\"name\":\"Expert opinion on investigational drugs\",\"volume\":\"80 1\",\"pages\":\"\"},\"PeriodicalIF\":4.9000,\"publicationDate\":\"2024-08-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Expert opinion on investigational drugs\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/13543784.2024.2388569\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Expert opinion on investigational drugs","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/13543784.2024.2388569","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
An overview of conventional and investigational phosphodiesterase 5 inhibitors for treating erectile dysfunction and other conditions
There is a rising concern about developing innovative, efficacious PDE5I molecules that provide better safety, efficacy and tolerability with less adverse effects. Innovative PDE5I with dual target...
期刊介绍：
Expert Opinion on Investigational Drugs (ISSN 1354-3784 [print], 1744-7658 [electronic]) is a MEDLINE-indexed, peer-reviewed, international journal publishing review articles and original papers on drugs in preclinical and early stage clinical development, providing expert opinion on the scope for future development.
The Editors welcome:
Reviews covering preclinical through to Phase II data on drugs or drug classes for specific indications, and their potential impact on future treatment strategies
Drug Evaluations reviewing the clinical and pharmacological data on a particular drug
Original Research papers reporting the results of clinical investigations on agents that are in Phase I and II clinical trials
The audience consists of scientists, managers and decision-makers in the pharmaceutical industry, and others closely involved in R&D.
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