241 名成人特应性皮炎患者瘙痒的昼夜节律:横断面研究

IF 3.5 4区 医学 Q1 DERMATOLOGY Acta dermato-venereologica Pub Date : 2024-08-05 DOI:10.2340/actadv.v104.35427
Xiaoxue Sang, Jianyun Lu, Lina Tan, Jinrong Zeng, Dan Wang, Aiyuan Guo, Siyuan Tang, Qian Zeng, Wei Liu, Lihua Gao
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引用次数: 0

摘要

特应性皮炎患者的瘙痒模式尚未得到系统研究。因此,本研究旨在评估成人特应性皮炎患者的瘙痒模式,采用问卷调查的方式,对一家机构的参与患者(n = 241)的瘙痒昼夜节律进行评估。该研究采用自我报告问卷来评估患者瘙痒的昼夜节律和强度。此外,还评估了患者的疾病严重程度(湿疹面积和严重程度指数[EASI])和生活质量(皮肤病生活质量指数[DLQI])。瘙痒发生频率最高(74.69%),严重程度最重(62.66%),发生时间为 20:00 至 00:00,而在 04:00 至 08:00 出现瘙痒的患者最少(25.31%)。DLQI 和 EASI 分数均与平均瘙痒强度和最大瘙痒强度相关(分别为 r = 0.582 和 r = 0.533;r = 0.539 和 r = 0.517; p
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The Circadian Rhythm of Itching among 241 Adults with Atopic Dermatitis: A Cross-sectional Study.

The pattern of itching in patients with atopic dermatitis has not been systematically studied. Therefore, this study aimed to assess the pattern of itching in adults with atopic dermatitis using questionnaires to assess for a circadian rhythm of itching in participating patients at a single institution (n = 241). A self-report questionnaire was used to assess circadian rhythm and intensity of itching in patients. In addition, the patients' disease severity (Eczema Area and Severity Index [EASI]) and quality of life (Dermatology Life Quality Index [DLQI]) were assessed. Itching occurred most frequently (74.69%) and with the greatest severity (62.66%) between 20:00 and 00:00, and the least number of patients (25.31%) experienced itching between 04:00 and 08:00. The DLQI and EASI scores both correlated with the average and maximum itch intensity (r = 0.582, r = 0.533, respectively; r = 0.539, r = 0.517, respectively; p < 0.001). The DLQI and EASI scores were associated with average itch intensity (B = 0.179, B = 0.204, respectively; 95% CI: 0.112 to 0.246, 95% CI: 0.096 to 0.313, respectively; p < 0.001), and the EASI score was associated with males and family history (B = 0.285, B = 0.287, respectively; 95% CI: 0.094 to 0.476, 95% CI: 0.096 to 0.478, respectively; p = 0.003). Adult patients with atopic dermatitis exhibited a circadian rhythm of itching; these study results could positively impact treatment approaches.

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来源期刊
Acta dermato-venereologica
Acta dermato-venereologica 医学-皮肤病学
CiteScore
4.90
自引率
2.80%
发文量
210
审稿时长
6-12 weeks
期刊介绍: Acta Dermato-Venereologica publishes high-quality manuscripts in English in the field of Dermatology and Venereology, dealing with new observations on basic dermatological and venereological research, as well as clinical investigations. Each volume also features a number of Review articles in special areas, as well as short Letters to the Editor to stimulate debate and to disseminate important clinical observations. Acta Dermato-Venereologica has rapid publication times and is amply illustrated with a large number of colour photographs.
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