性腺发育不良患者的尼罗罗非鱼皮移植阴道成形术：病例报告。

IF 1.7 4区医学 Q3 OBSTETRICS & GYNECOLOGY Journal of pediatric and adolescent gynecology Pub Date : 2024-08-02 DOI:10.1016/j.jpag.2024.07.008

Samuel Soares Coutinho, Luana Darc de Menezes Braga, Mylena Evilyn Sousa Costa, Mariana Oliveira Veloso, Ana Paula Negreiros Nunes Alves, Edmar Maciel Lima Júnior, Zenilda Vieira Bruno, Manoel Odorico de Moraes Filho, Carlos Roberto Koscky Paier, Felipe Augusto Rocha Rodrigues, Leonardo Robson Pinheiro Sobreira Bezerra

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引用次数: 0

摘要

背景：性腺发育不良是一种遗传性疾病，其特点是性腺形成不完全或有缺陷，46,XY 核型患者可能会出现阴道发育不良：我们报告了在治疗一名患有性腺发育不良的 19 岁女性阴道无阴道症时所采取的创新干预措施。尽管最初尝试过使用阴道扩张器，但患者没有任何反应，因此我们采用了尼罗罗非鱼皮（NTFS）作为移植物的阴道成形术。该手术以 McIndoe 技术为基础，用包裹 NTFS 的丙烯酸模具创建了一个 10 厘米 x 3 厘米的阴道，没有出现并发症：讨论：在性腺发育不良患者的阴道成形术中使用 NTFS 作为移植物，是医学文献中从未报道过的一种新方法。

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Neovaginoplasty With Nile Tilapia Skin Graft in A Patient With Gonadal Dysgenesis: A Case Report.

Background: Gonadal dysgenesis, a genetic condition characterized by incomplete of defective formation of the gonads, can present with vaginal agenesis in individuals with 46, XY karyotype.

Case: We report an innovative intervention in the management of vaginal agenesis in a 19-year-old female with gonadal dysgenesis. Despite initial attempts with vaginal dilators, the patient presented unresponsive, leading to the adoption of a neovaginoplasty using Nile Tilapia Fish Skin (NTFS) as graft. The procedure, based on the McIndoe technique, involved the creation of a 10 cm x 3 cm vaginal canal with an NTFS-wrapped acrylic mold without complications.

Conclusion: The use of NTFS as a graft for neovaginoplasty in gonadal dysgenesis, a novel approach not previously reported in medical literature for this diagnosis, demonstrated favorable outcomes in terms of functionality and patient well-being.

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来源期刊

Journal of pediatric and adolescent gynecology 医学-妇产科学

CiteScore

3.90

自引率

11.10%

发文量

251

审稿时长

57 days

期刊介绍： Journal of Pediatric and Adolescent Gynecology includes all aspects of clinical and basic science research in pediatric and adolescent gynecology. The Journal draws on expertise from a variety of disciplines including pediatrics, obstetrics and gynecology, reproduction and gynecology, reproductive and pediatric endocrinology, genetics, and molecular biology. The Journal of Pediatric and Adolescent Gynecology features original studies, review articles, book and literature reviews, letters to the editor, and communications in brief. It is an essential resource for the libraries of OB/GYN specialists, as well as pediatricians and primary care physicians.