利用准可能性中的融合惩罚对医疗服务提供者进行聚类。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-08-05 DOI:10.1002/bimj.202300185
Lili Liu, Kevin He, Di Wang, Shujie Ma, Annie Qu, Yihui Luan, J. Philip Miller, Yizhe Song, Lei Liu
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引用次数: 0

摘要

研究人员对开发评估医疗服务提供者在患者治疗结果方面表现的方法越来越感兴趣。传统上,随机效应和固定效应模型被用于此目的。我们提出了一种新方法,使用融合惩罚来根据准可能性对医疗服务提供者进行分组。在不预先了解分组信息的情况下,我们的方法提供了一种理想的数据驱动方法,可根据医疗服务提供者的表现自动将其分为不同的组别。此外,准似然法比常规似然法更灵活、更稳健,因为它不需要分布假设。为了实现所提出的方法,我们开发了一种高效的交替方向乘法算法。我们证明了所提出的方法具有神谕特性,即它的性能与事先已知的真实群体结构一样好。我们还确定了估计值的一致性和渐近正态性。模拟研究和全国肾移植登记数据分析证明了我们方法的实用性和有效性。
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Health Care Provider Clustering Using Fusion Penalty in Quasi-Likelihood

There has been growing research interest in developing methodology to evaluate the health care providers' performance with respect to a patient outcome. Random and fixed effects models are traditionally used for such a purpose. We propose a new method, using a fusion penalty to cluster health care providers based on quasi-likelihood. Without any priori knowledge of grouping information, our method provides a desirable data-driven approach for automatically clustering health care providers into different groups based on their performance. Further, the quasi-likelihood is more flexible and robust than the regular likelihood in that no distributional assumption is needed. An efficient alternating direction method of multipliers algorithm is developed to implement the proposed method. We show that the proposed method enjoys the oracle properties; namely, it performs as well as if the true group structure were known in advance. The consistency and asymptotic normality of the estimators are established. Simulation studies and analysis of the national kidney transplant registry data demonstrate the utility and validity of our method.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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