免疫力低下患者因耐药万古霉素肠球菌血源性传播引发细菌性脑膜炎的罕见病例。

IF 1 Q4 INFECTIOUS DISEASES Case Reports in Infectious Diseases Pub Date : 2024-07-25 eCollection Date: 2024-01-01 DOI:10.1155/2024/2193650
Myeongji Kim, Christopher Graham, Ryan W Stevens, Aditya Shah
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引用次数: 0

摘要

耐万古霉素粪肠球菌(VRE)脑膜炎非常罕见。它通常与神经外科手术或装置有关。我们描述了一例因 VEXAS 综合征而接受单倍体骨髓移植的免疫功能低下患者在持续菌血症期间因血源性传播而引发 VRE 脑膜炎的病例。通过静脉注射达托霉素、头孢他啶和利奈唑胺成功治疗了菌血症和脑膜炎。
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A Rare Case of Bacterial Meningitis Caused by Hematogenous Spread of Vancomycin-Resistant Enterococcus faecium in an Immunocompromised Patient.

Vancomycin-resistant Enterococcus faecium (VRE) meningitis is rare. It is usually associated with neurosurgical procedures or devices. We describe a case of VRE meningitis from hematogenous spread during persistent bacteremia in an immunocompromised patient who received haploidentical bone marrow transplant for VEXAS syndrome. The bacteremia and meningitis were successfully treated with combination of intravenous (IV) daptomycin, ceftaroline, and linezolid.

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