一名免疫功能正常儿童胸骨肿胀所显示的多灶性肺结核。

Access microbiology Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI:10.1099/acmi.0.000795.v3
Ghizlane Chehrastane, Elmostafa Benaissa, Abdelilah Radi, Amal El Hassani, Mostafa Elouennass
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引用次数: 0

摘要

结核病(TB)是细菌性肺部感染最常见的病原体之一,尤其是在像摩洛哥这样的欠发达国家,2019 年的结核病发病率为每 10 万人 97 例。得益于国家结核病防控计划,摩洛哥得以在结核病管理方面取得显著进展,1980 年至 2018 年间,确诊的结核病患者总数减少了 80%。自 2002 年以来,该国家计划还使我们的治疗率达到并保持在 86% 以上。胸骨结核是一种罕见的临床病症,占所有肌肉骨骼结核病例的 1%。由于其罕见性和缺乏对临床表现的认识,胸骨结核的诊断可能相当复杂。我们描述了这样一个病例:一名 14 岁的摩洛哥患者在穆罕默德五世-拉巴特军事医院就诊,胸痛持续 4 个月,与呼吸、运动或进食无关。患者还有气喘、发烧和体重减轻的病史。胸部计算机断层扫描显示胸骨有破坏性病变。随后,进行了外科活检,并通过实时 PCR 确定了结核病的微生物学诊断。患者接受了抗结核治疗,症状完全缓解。这种情况应被纳入模仿肋软骨炎的慢性胸痛的鉴别诊断中,尤其是来自地方病流行地区的患者。
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Multifocal tuberculosis revealed by a sternal swelling in an immunocompetent child.

Tuberculosis (TB) is one of the most common pathogens of bacterial lung infections, especially in underdeveloped nations like Morocco, where the incidence of TB was 97 cases per 100 000 persons in 2019. Thanks to its national TB prevention and control plan, Morocco was able to achieve remarkable progress in the management of TB with an 80% reduction in the total number of patients diagnosed with TB between 1980 and 2018. The national plan also allowed us to reach and maintain a therapeutic rate above 86% since 2002. Sternal TB is a rare clinical condition accounting for 1% of all musculoskeletal TB cases. Due to its rarity and the lack of awareness of clinical presentations, the diagnosis of sternal TB can be quite complex. We describe the case of a 14-year-old Moroccan patient consulting in the Military Hospital Mohammed V-Rabat with central chest pain for 4 months which was not associated with breathing, physical exercise or eating. The patient also had a history of asthenia, fever and weight loss. A computed tomography scan of the chest showed a destructive lesion of the sternum. Afterward, a chirurgical biopsy was performed and enabled to confirm the microbiological diagnosis of TB with the realization of the real-time PCR. The antitubercular therapy was given to the patient who had complete resolution of symptoms. This condition should be included in the differential diagnosis of chronic chest pain that mimics costochondritis particularly in patients from endemic areas.

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