Abdallah M Elkhouly, Maram Y Baldam, Shaimaa Al-Touny, Amany S Almeanawy, Mohamed N Abohalawa, Mahmoud Hamed, Fotouh R Mansour
{"title":"埃及种植的具有抗病毒潜力的药用植物:系统综述。","authors":"Abdallah M Elkhouly, Maram Y Baldam, Shaimaa Al-Touny, Amany S Almeanawy, Mohamed N Abohalawa, Mahmoud Hamed, Fotouh R Mansour","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Viral diseases are a worldwide concern as some of them are associated with unexpectedly high mortality rates. Common viruses include e.g., Influenza virus, HIV, hepatitis viruses, and recently COVID-19. Many viral diseases are still incurable by conventional antiviral drugs. Moreover, the emergence of resistant viral strains has reinforced the search for other alternatives. In ancient times, herbal therapy was commonly used where medicinal formulations were created from various plants. In recent times, in vitro, in vivo, animal studies, and clinical trials have revealed the antiviral properties of these plants, sparking hope for the treatment of serious viral diseases. The present review aims to summarize studies that focus on medicinal plants available in Egypt with antiviral properties.</p><p><strong>Methods: </strong>The articles published in English between 1988 and 2022 and available in PubMed and Scopus databases with the relevant keywords were included.</p><p><strong>Results: </strong>Thirty-two plants in Egypt have met the criteria and possess in vitro or in vivo antiviral activity via different mechanisms. Only five of them; Camellia sinensis, Marine algae, Zizyphus spina-christi L., Trachyspermum Ammi, and Aloe Vera have been proven to be effective in vivo. For COVID-19, thirteen plants have shown efficacy against SARS-Cov-2 via different mechanisms including Camellia sinensis, Cinnamomum Verum, Punica granatum, Glycyrrhiza glabra, Zingiber officinale, Curcuma longa, Marine algae, Phlomis aurea oil, Solanum nigrum, Trachyspermum Ammi, Arum palaestinum, Aloe Vera, and Cyperus rotundus.</p><p><strong>Conclusion: </strong>This review summarizes the current scientific evidence on 32 medicinal plant species cultivated in Egypt that have demonstrated antiviral properties against various DNA and RNA viruses through in vitro and in vivo studies, highlighting their potential as prospective sources for the development of novel antiviral therapies. Further clinical research is still warranted to validate the effectiveness and safety of these plants as complementary treatment options for viral infections.</p>","PeriodicalId":7571,"journal":{"name":"Alternative therapies in health and medicine","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Medicinal Plants Cultivated in Egypt with Antiviral Potential: A Systematic Review.\",\"authors\":\"Abdallah M Elkhouly, Maram Y Baldam, Shaimaa Al-Touny, Amany S Almeanawy, Mohamed N Abohalawa, Mahmoud Hamed, Fotouh R Mansour\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Viral diseases are a worldwide concern as some of them are associated with unexpectedly high mortality rates. Common viruses include e.g., Influenza virus, HIV, hepatitis viruses, and recently COVID-19. Many viral diseases are still incurable by conventional antiviral drugs. Moreover, the emergence of resistant viral strains has reinforced the search for other alternatives. In ancient times, herbal therapy was commonly used where medicinal formulations were created from various plants. In recent times, in vitro, in vivo, animal studies, and clinical trials have revealed the antiviral properties of these plants, sparking hope for the treatment of serious viral diseases. The present review aims to summarize studies that focus on medicinal plants available in Egypt with antiviral properties.</p><p><strong>Methods: </strong>The articles published in English between 1988 and 2022 and available in PubMed and Scopus databases with the relevant keywords were included.</p><p><strong>Results: </strong>Thirty-two plants in Egypt have met the criteria and possess in vitro or in vivo antiviral activity via different mechanisms. Only five of them; Camellia sinensis, Marine algae, Zizyphus spina-christi L., Trachyspermum Ammi, and Aloe Vera have been proven to be effective in vivo. For COVID-19, thirteen plants have shown efficacy against SARS-Cov-2 via different mechanisms including Camellia sinensis, Cinnamomum Verum, Punica granatum, Glycyrrhiza glabra, Zingiber officinale, Curcuma longa, Marine algae, Phlomis aurea oil, Solanum nigrum, Trachyspermum Ammi, Arum palaestinum, Aloe Vera, and Cyperus rotundus.</p><p><strong>Conclusion: </strong>This review summarizes the current scientific evidence on 32 medicinal plant species cultivated in Egypt that have demonstrated antiviral properties against various DNA and RNA viruses through in vitro and in vivo studies, highlighting their potential as prospective sources for the development of novel antiviral therapies. Further clinical research is still warranted to validate the effectiveness and safety of these plants as complementary treatment options for viral infections.</p>\",\"PeriodicalId\":7571,\"journal\":{\"name\":\"Alternative therapies in health and medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Alternative therapies in health and medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INTEGRATIVE & COMPLEMENTARY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alternative therapies in health and medicine","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
Medicinal Plants Cultivated in Egypt with Antiviral Potential: A Systematic Review.
Background: Viral diseases are a worldwide concern as some of them are associated with unexpectedly high mortality rates. Common viruses include e.g., Influenza virus, HIV, hepatitis viruses, and recently COVID-19. Many viral diseases are still incurable by conventional antiviral drugs. Moreover, the emergence of resistant viral strains has reinforced the search for other alternatives. In ancient times, herbal therapy was commonly used where medicinal formulations were created from various plants. In recent times, in vitro, in vivo, animal studies, and clinical trials have revealed the antiviral properties of these plants, sparking hope for the treatment of serious viral diseases. The present review aims to summarize studies that focus on medicinal plants available in Egypt with antiviral properties.
Methods: The articles published in English between 1988 and 2022 and available in PubMed and Scopus databases with the relevant keywords were included.
Results: Thirty-two plants in Egypt have met the criteria and possess in vitro or in vivo antiviral activity via different mechanisms. Only five of them; Camellia sinensis, Marine algae, Zizyphus spina-christi L., Trachyspermum Ammi, and Aloe Vera have been proven to be effective in vivo. For COVID-19, thirteen plants have shown efficacy against SARS-Cov-2 via different mechanisms including Camellia sinensis, Cinnamomum Verum, Punica granatum, Glycyrrhiza glabra, Zingiber officinale, Curcuma longa, Marine algae, Phlomis aurea oil, Solanum nigrum, Trachyspermum Ammi, Arum palaestinum, Aloe Vera, and Cyperus rotundus.
Conclusion: This review summarizes the current scientific evidence on 32 medicinal plant species cultivated in Egypt that have demonstrated antiviral properties against various DNA and RNA viruses through in vitro and in vivo studies, highlighting their potential as prospective sources for the development of novel antiviral therapies. Further clinical research is still warranted to validate the effectiveness and safety of these plants as complementary treatment options for viral infections.
期刊介绍:
Launched in 1995, Alternative Therapies in Health and Medicine has a mission to promote the art and science of integrative medicine and a responsibility to improve public health. We strive to maintain the highest standards of ethical medical journalism independent of special interests that is timely, accurate, and a pleasure to read. We publish original, peer-reviewed scientific articles that provide health care providers with continuing education to promote health, prevent illness, and treat disease. Alternative Therapies in Health and Medicine was the first journal in this field to be indexed in the National Library of Medicine. In 2006, 2007, and 2008, ATHM had the highest impact factor ranking of any independently published peer-reviewed CAM journal in the United States—meaning that its research articles were cited more frequently than any other journal’s in the field.
Alternative Therapies in Health and Medicine does not endorse any particular system or method but promotes the evaluation and appropriate use of all effective therapeutic approaches. Each issue contains a variety of disciplined inquiry methods, from case reports to original scientific research to systematic reviews. The editors encourage the integration of evidence-based emerging therapies with conventional medical practices by licensed health care providers in a way that promotes a comprehensive approach to health care that is focused on wellness, prevention, and healing. Alternative Therapies in Health and Medicine hopes to inform all licensed health care practitioners about developments in fields other than their own and to foster an ongoing debate about the scientific, clinical, historical, legal, political, and cultural issues that affect all of health care.