在澳大利亚全科医生中实施药物基因组测试:一项探索性定性研究。

IF 1.9 4区 医学 Q3 PHARMACOLOGY & PHARMACY Pharmacogenomics Pub Date : 2024-01-01 Epub Date: 2024-08-07 DOI:10.1080/14622416.2024.2382078
Emma Ewasiuk, Jon Emery, Gabrielle Reid, Sibel Saya
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引用次数: 0

摘要

目的:探讨全科医生(GPs)对在澳大利亚全科实践中实施药物基因组学检测的看法。方法:从初级保健网络中招募了九名澳大利亚全科医生,对他们进行了半结构化访谈:对从初级保健网络中招募的九名澳大利亚全科医生进行了半结构化访谈。采用主题分析法对访谈进行了分析。将主题映射到实施研究领域综合框架中。结果显示实施障碍包括缺乏知识、教育、标准化药物基因组学报告和国家临床指南,以及经济上的不便。促进因素包括积极接触药物基因组学、同行影响、跨学科合作以及经证实的临床效用。然而,全科医生都对临床应用持积极态度。结论:成功实施的建议包括建立和传播临床证据、制定国家指南和标准化报告、将其纳入正规教育以及提高经济可及性。
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Implementing pharmacogenomic testing in Australian general practice: an exploratory qualitative study.

Aim: To explore general practitioners' (GPs) views on implementing pharmacogenomic testing in Australian general practice.Methods: Semi-structured interviews were conducted with nine GPs in Australia, recruited from primary care networks. Interviews were analyzed using thematic analysis. Themes were mapped onto the Consolidated Framework for Implementation Research domains.Results: Barriers to implementation included lack of knowledge, education, standardized pharmacogenomic reports and national clinical guidelines and financial inaccessibility. Facilitators included positive exposure to pharmacogenomics, peer influences, interdisciplinary collaboration and proven clinical utility. Current uptake was minimal; however, GPs shared positive perceptions of clinical use.Conclusion: Recommendations for successful implementation include building and disseminating clinical evidence, developing national guidelines and standardized reports, incorporation into formal education and increasing financial accessibility.

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来源期刊
Pharmacogenomics
Pharmacogenomics 医学-药学
CiteScore
3.40
自引率
9.50%
发文量
88
审稿时长
4-8 weeks
期刊介绍: Pharmacogenomics (ISSN 1462-2416) is a peer-reviewed journal presenting reviews and reports by the researchers and decision-makers closely involved in this rapidly developing area. Key objectives are to provide the community with an essential resource for keeping abreast of the latest developments in all areas of this exciting field. Pharmacogenomics is the leading source of commentary and analysis, bringing you the highest quality expert analyses from corporate and academic opinion leaders in the field.
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