用斑块近距离放射治疗原发性结膜基底细胞癌:一例罕见病例报告。

Pub Date : 2024-08-07 DOI:10.1080/01676830.2024.2387094
Adwaita Nag, Hatem Krema, Zaid Saeed Kamil, Beiki-Ardakani Akbar, Normand Laperriere
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引用次数: 0

摘要

结膜原发性基底细胞癌(BCC)是一种罕见肿瘤,文献中仅有六例报道。本病例是一名 81 岁的男性,主诉其右眼在过去 3 年中出现缓慢生长的病变。病变位于颞部球结膜,呈胶状,与巩膜紧密粘连。超声生物显微镜检查显示巩膜明显变薄,但无侵犯。我们的初步诊断是眼表面鳞状上皮瘤,但切开活检进行组织病理学诊断后发现这是一个 BCC。由于巩膜粘连和变薄,病变无法进行手术切除。我们采用斑块近距离放射疗法成功治疗了病灶。据我们所知,这是第一例近距离放射治疗这种罕见癌症的报告。此前报道的病例均为结节型或梗阻型,采用手术切除治疗。对于扁平、粘连或浸润性病灶,斑块近距离放射治疗是一种有效的主要治疗方式。
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Primary conjunctival basal cell carcinoma treated with plaque brachytherapy: a rare case report.

Primary basal cell carcinoma (BCC) of the conjunctiva is a rare tumor with only six cases reported in literature. We present the case of an 81-year-old male complaining of a slow-growing lesion in his right eye for the past 3 years. The lesion in the temporal bulbar conjunctiva was gelatinous and firmly adherent to sclera. Ultrasound biomicroscopy revealed apparent scleral thinning without invasion. Our provisional diagnosis was ocular surface squamous neoplasia; however, incisional biopsy for histopathological diagnosis revealed that it was a BCC. Due to scleral adhesion and thinning, the lesion was not amenable for surgical resection. Plaque brachytherapy was used to successfully treat the lesion. To the best of our knowledge, this is the first report of brachytherapy administration for treatment of this rare cancer. Previously reported cases were all nodular or pedunculated and treated with surgical excision. For flat, adherent, or invasive lesions, plaque brachytherapy is an effective primary treatment modality.

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