{"title":"青少年精神病的发病率和风险:探索童年创伤作用的前瞻性队列研究(HUNT 研究)。","authors":"Helle Stangeland, Helene Flood Aakvaag, Monica Baumann-Larsen, Tore Wentzel-Larsen, Akiah Ottesen, John Anker Zwart, Kjersti Storheim, Grete Dyb, Synne Øien Stensland","doi":"10.1192/bjp.2024.98","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Better knowledge about childhood trauma as a risk factor for psychiatric disorders in young people could help strengthen the timeliness and effectiveness of prevention and treatment efforts.</p><p><strong>Aims: </strong>To estimate the prevalence and risk of psychiatric disorders in young people following exposure to childhood trauma, including interpersonal violence.</p><p><strong>Method: </strong>This prospective cohort study followed 8199 adolescents (age range 12-20 years) over 13-15 years, into young adulthood (age range 25-35 years). Data about childhood trauma exposure from adolescents participating in the Trøndelag Health Study (HUNT, 2006-2008) were linked to data about subsequent development of psychiatric disorders from the Norwegian Patient Registry (2008-2021).</p><p><strong>Results: </strong>One in four (24.3%) adolescents were diagnosed with a psychiatric disorder by young adulthood. Regression analyses showed consistent and significant relationships between childhood exposure to both interpersonal violence and other potentially traumatic events, and subsequent psychiatric disorders and psychiatric comorbidity. The highest estimates were observed for childhood exposure to two or more types of interpersonal violence (polyvictimisation), and development of psychotic disorders (odds ratio 3.41, 95% CI 1.93-5.72), stress and adjustment disorders (odds ratio 4.20, 95% CI 3.05-5.71), personality disorders (odds ratio 3.98, 95% CI 2.70-5.76), alcohol-related disorders (odds ratio 3.28, 95% CI 2.06-5.04) and drug-related disorders (odds ratio 4.67, 95% CI 2.87-7.33).</p><p><strong>Conclusions: </strong>These findings emphasise the importance of integrating knowledge about childhood trauma as a potent risk factor for psychopathology into the planning and implementation of services for children, adolescents and young adults.</p>","PeriodicalId":9259,"journal":{"name":"British Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":8.7000,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalence and risk of psychiatric disorders in young people: prospective cohort study exploring the role of childhood trauma (the HUNT study).\",\"authors\":\"Helle Stangeland, Helene Flood Aakvaag, Monica Baumann-Larsen, Tore Wentzel-Larsen, Akiah Ottesen, John Anker Zwart, Kjersti Storheim, Grete Dyb, Synne Øien Stensland\",\"doi\":\"10.1192/bjp.2024.98\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Better knowledge about childhood trauma as a risk factor for psychiatric disorders in young people could help strengthen the timeliness and effectiveness of prevention and treatment efforts.</p><p><strong>Aims: </strong>To estimate the prevalence and risk of psychiatric disorders in young people following exposure to childhood trauma, including interpersonal violence.</p><p><strong>Method: </strong>This prospective cohort study followed 8199 adolescents (age range 12-20 years) over 13-15 years, into young adulthood (age range 25-35 years). Data about childhood trauma exposure from adolescents participating in the Trøndelag Health Study (HUNT, 2006-2008) were linked to data about subsequent development of psychiatric disorders from the Norwegian Patient Registry (2008-2021).</p><p><strong>Results: </strong>One in four (24.3%) adolescents were diagnosed with a psychiatric disorder by young adulthood. Regression analyses showed consistent and significant relationships between childhood exposure to both interpersonal violence and other potentially traumatic events, and subsequent psychiatric disorders and psychiatric comorbidity. The highest estimates were observed for childhood exposure to two or more types of interpersonal violence (polyvictimisation), and development of psychotic disorders (odds ratio 3.41, 95% CI 1.93-5.72), stress and adjustment disorders (odds ratio 4.20, 95% CI 3.05-5.71), personality disorders (odds ratio 3.98, 95% CI 2.70-5.76), alcohol-related disorders (odds ratio 3.28, 95% CI 2.06-5.04) and drug-related disorders (odds ratio 4.67, 95% CI 2.87-7.33).</p><p><strong>Conclusions: </strong>These findings emphasise the importance of integrating knowledge about childhood trauma as a potent risk factor for psychopathology into the planning and implementation of services for children, adolescents and young adults.</p>\",\"PeriodicalId\":9259,\"journal\":{\"name\":\"British Journal of Psychiatry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":8.7000,\"publicationDate\":\"2024-08-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British Journal of Psychiatry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1192/bjp.2024.98\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British Journal of Psychiatry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1192/bjp.2024.98","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
摘要
背景:更好地了解童年创伤作为青少年精神障碍的一个风险因素,有助于加强预防和治疗工作的及时性和有效性。目的:估算遭受童年创伤(包括人际暴力)后青少年精神障碍的患病率和风险:这项前瞻性队列研究对 8199 名青少年(年龄在 12-20 岁之间)进行了长达 13-15 年的跟踪调查,直至他们进入青年期(年龄在 25-35 岁之间)。参与特伦德拉格健康研究(HUNT,2006-2008年)的青少年所提供的童年创伤数据,与挪威患者登记(2008-2021年)中有关青少年随后患上精神疾病的数据相联系:每四名青少年中就有一人(24.3%)在成年后被诊断患有精神疾病。回归分析表明,童年时期遭受的人际暴力和其他潜在创伤事件与后来的精神障碍和精神疾病合并症之间存在着一致且显著的关系。童年时期遭受两种或两种以上类型的人际暴力(多重伤害)、精神障碍(几率比 3.41,95% CI 1.93-5.72)、压力和适应障碍(几率比 4.20,95% CI 3.93-5.72)的估计值最高。20,95% CI 3.05-5.71)、人格障碍(几率比 3.98,95% CI 2.70-5.76)、酒精相关障碍(几率比 3.28,95% CI 2.06-5.04)和毒品相关障碍(几率比 4.67,95% CI 2.87-7.33):这些研究结果强调,在规划和实施针对儿童、青少年和年轻成人的服务时,必须了解童年创伤是导致精神病理学的潜在风险因素。
Prevalence and risk of psychiatric disorders in young people: prospective cohort study exploring the role of childhood trauma (the HUNT study).
Background: Better knowledge about childhood trauma as a risk factor for psychiatric disorders in young people could help strengthen the timeliness and effectiveness of prevention and treatment efforts.
Aims: To estimate the prevalence and risk of psychiatric disorders in young people following exposure to childhood trauma, including interpersonal violence.
Method: This prospective cohort study followed 8199 adolescents (age range 12-20 years) over 13-15 years, into young adulthood (age range 25-35 years). Data about childhood trauma exposure from adolescents participating in the Trøndelag Health Study (HUNT, 2006-2008) were linked to data about subsequent development of psychiatric disorders from the Norwegian Patient Registry (2008-2021).
Results: One in four (24.3%) adolescents were diagnosed with a psychiatric disorder by young adulthood. Regression analyses showed consistent and significant relationships between childhood exposure to both interpersonal violence and other potentially traumatic events, and subsequent psychiatric disorders and psychiatric comorbidity. The highest estimates were observed for childhood exposure to two or more types of interpersonal violence (polyvictimisation), and development of psychotic disorders (odds ratio 3.41, 95% CI 1.93-5.72), stress and adjustment disorders (odds ratio 4.20, 95% CI 3.05-5.71), personality disorders (odds ratio 3.98, 95% CI 2.70-5.76), alcohol-related disorders (odds ratio 3.28, 95% CI 2.06-5.04) and drug-related disorders (odds ratio 4.67, 95% CI 2.87-7.33).
Conclusions: These findings emphasise the importance of integrating knowledge about childhood trauma as a potent risk factor for psychopathology into the planning and implementation of services for children, adolescents and young adults.
期刊介绍:
The British Journal of Psychiatry (BJPsych) is a renowned international journal that undergoes rigorous peer review. It covers various branches of psychiatry, with a specific focus on the clinical aspects of each topic. Published monthly by the Royal College of Psychiatrists, this journal is dedicated to enhancing the prevention, investigation, diagnosis, treatment, and care of mental illness worldwide. It also strives to promote global mental health. In addition to featuring authoritative original research articles from across the globe, the journal includes editorials, review articles, commentaries on contentious issues, a comprehensive book review section, and a dynamic correspondence column. BJPsych is an essential source of information for psychiatrists, clinical psychologists, and other professionals interested in mental health.