{"title":"日本秋田县镉污染区的疑似 \"itai-itai 病 \"病例。","authors":"Toru Sasaki, Hyogo Horiguchi, Takehisa Matsukawa, Momoko Kobayashi, Yuki Omori, Etsuko Oguma, Atsushi Komatsuda","doi":"10.1265/ehpm.24-00063","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Itai-itai disease is the most severe case of chronic cadmium (Cd) toxicity, which was endemic in Cd-polluted areas in the Jinzu River basin in Toyama prefecture, Japan. Akita prefecture also has Cd-polluted areas, but there have been no cases of \"itai-itai disease\".</p><p><strong>Case presentation: </strong>An elderly female farmer with Cd nephropathy residing in a Cd-polluted area in the northern part of the Akita prefecture was identified through hospital-based screening at Akita Rosai Hospital in Odate city. She had chronic renal failure with a high Cd exposure level and advanced renal tubular dysfunction. The shortening of height, bone deformities and fractures, abnormal bone metabolism suggesting osteomalacia, and renal anemia were also noted. Therefore, \"itai-itai disease\", similar to cases in the Jinzu River basin, was suspected.</p><p><strong>Conclusion: </strong>This is the first case of \"itai-itai disease\" in a Cd-polluted area in Akita prefecture.</p>","PeriodicalId":11707,"journal":{"name":"Environmental Health and Preventive Medicine","volume":"29 ","pages":"40"},"PeriodicalIF":4.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11310559/pdf/","citationCount":"0","resultStr":"{\"title\":\"A suspected case of \\\"itai-itai disease\\\" in a cadmium-polluted area in Akita prefecture, Japan.\",\"authors\":\"Toru Sasaki, Hyogo Horiguchi, Takehisa Matsukawa, Momoko Kobayashi, Yuki Omori, Etsuko Oguma, Atsushi Komatsuda\",\"doi\":\"10.1265/ehpm.24-00063\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Itai-itai disease is the most severe case of chronic cadmium (Cd) toxicity, which was endemic in Cd-polluted areas in the Jinzu River basin in Toyama prefecture, Japan. Akita prefecture also has Cd-polluted areas, but there have been no cases of \\\"itai-itai disease\\\".</p><p><strong>Case presentation: </strong>An elderly female farmer with Cd nephropathy residing in a Cd-polluted area in the northern part of the Akita prefecture was identified through hospital-based screening at Akita Rosai Hospital in Odate city. She had chronic renal failure with a high Cd exposure level and advanced renal tubular dysfunction. The shortening of height, bone deformities and fractures, abnormal bone metabolism suggesting osteomalacia, and renal anemia were also noted. Therefore, \\\"itai-itai disease\\\", similar to cases in the Jinzu River basin, was suspected.</p><p><strong>Conclusion: </strong>This is the first case of \\\"itai-itai disease\\\" in a Cd-polluted area in Akita prefecture.</p>\",\"PeriodicalId\":11707,\"journal\":{\"name\":\"Environmental Health and Preventive Medicine\",\"volume\":\"29 \",\"pages\":\"40\"},\"PeriodicalIF\":4.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11310559/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Environmental Health and Preventive Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1265/ehpm.24-00063\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental Health and Preventive Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1265/ehpm.24-00063","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
A suspected case of "itai-itai disease" in a cadmium-polluted area in Akita prefecture, Japan.
Background: Itai-itai disease is the most severe case of chronic cadmium (Cd) toxicity, which was endemic in Cd-polluted areas in the Jinzu River basin in Toyama prefecture, Japan. Akita prefecture also has Cd-polluted areas, but there have been no cases of "itai-itai disease".
Case presentation: An elderly female farmer with Cd nephropathy residing in a Cd-polluted area in the northern part of the Akita prefecture was identified through hospital-based screening at Akita Rosai Hospital in Odate city. She had chronic renal failure with a high Cd exposure level and advanced renal tubular dysfunction. The shortening of height, bone deformities and fractures, abnormal bone metabolism suggesting osteomalacia, and renal anemia were also noted. Therefore, "itai-itai disease", similar to cases in the Jinzu River basin, was suspected.
Conclusion: This is the first case of "itai-itai disease" in a Cd-polluted area in Akita prefecture.
期刊介绍:
The official journal of the Japanese Society for Hygiene, Environmental Health and Preventive Medicine (EHPM) brings a comprehensive approach to prevention and environmental health related to medical, biological, molecular biological, genetic, physical, psychosocial, chemical, and other environmental factors.
Environmental Health and Preventive Medicine features definitive studies on human health sciences and provides comprehensive and unique information to a worldwide readership.