及时剃须刀治疗可去除慢性顶部肿块,改善手术效果。

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-07-09 eCollection Date: 2024-01-01 DOI:10.7150/ijms.95372
Patrick Szu-Ying Yen, Hung-Pin Tu, Shu-Hung Huang, Su-Shin Lee
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引用次数: 0

摘要

背景:目前的降尿酸盐疗法(ULT)对大多数痛风患者有效。然而,其中约有 10% 的患者对 ULT 反应不佳,出现慢性痛风病灶。研究目的本研究旨在评估刨削术对慢性痛风病灶的疗效。研究方法这项单中心、回顾性队列研究纳入了 217 名患者,他们在 2002 年至 2018 年间累计接受了 303 次刨削术辅助手术。手术结果根据住院时间(LOS)和伤口愈合时间进行评估。结果显示与无感染和上肢有病变的患者相比,术前上肢感染和下肢有病变的患者的住院时间和伤口愈合时间更长(分别为住院时间:12.7 天 vs. 8.6 天;伤口愈合时间:22.7 天 vs. 16.3 天)。然而,年龄、性别、体重指数、肾功能或尿毒症水平等因素对手术结果没有显著影响。结论涉及刨削术的手术应在上皮感染前进行。上肢病变的临床疗效往往优于下肢病变。
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Timely Shaver Treatment Removes Chronic Tophaceous Mass Improve Surgical Outcomes.

Background: Current treatments with urate-lowering therapy (ULT) are effective for most patients with gout. However, approximately 10% of these patients do not respond well to ULT and develop chronic tophus lesions. Objective: This study aimed to evaluate the efficacy of surgery involving the shaver technique against chronic tophus lesions. Methods: This single-center, retrospective cohort study included 217 patients who had cumulatively undergone 303 shaver-assisted procedures between 2002 and 2018. Surgical outcomes were assessed in terms of the length of hospital stay (LOS) and wound healing time. Results: LOS and wound healing time were longer in patients with a preoperative tophus infection and lower extremity lesions than in those without infection and with upper extremity lesions (respectively, LOS: 12.7 vs. 8.6 days; wound healing time: 22.7 vs. 16.3 days). However, factors such as age, sex, body mass index, renal function, or uricemia level exerted no significant effect on surgical outcomes. Conclusion: Surgery involving the shaver technique should be performed before tophus infection. Clinical outcomes tend to be better for upper extremity lesions than for lower extremity lesions.

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