肺立体定向体放射治疗 13 年后观察到的伴有病理性肋骨骨折的骨肿瘤样胸壁肿块病变:病例报告。

IF 2.3 3区 医学 Q3 ONCOLOGY Thoracic Cancer Pub Date : 2024-09-01 Epub Date: 2024-08-07 DOI:10.1111/1759-7714.15419
Masaki Matsuda, Jiro Ichikawa, Takafumi Komiyama, Kojiro Onohara, Masahide Saito, Hikaru Nemoto, Mizuki Kubota, Hiroshi Onishi
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引用次数: 0

摘要

尽管立体定向体放射治疗(SBRT)是治疗 I 期非小细胞肺癌(NSCLC)的一种治愈性治疗方法,但在超过 10 年的长期随访过程中,有关胸壁(CW)毒性的数据非常有限。我们报告了一例不寻常的病例,患者在接受 SBRT 治疗周围型肺癌 13 年后出现骨肿瘤样 CW 肿块病变,并伴有病理性肋骨骨折。尽管最初怀疑是放射诱导的肉瘤,但随后的切口活检未发现恶性证据,最终确诊为骨坏死。因此,需要进行10年以上的长期观察,以确定SBRT术后的晚期慢性并发症。
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A bone tumor-like chest wall mass lesion with pathological rib fractures observed 13 years after lung stereotactic body radiotherapy: A case report.

Although stereotactic body radiotherapy (SBRT) is a curative treatment option for stage I non-small cell lung cancer (NSCLC), limited data are available regarding chest wall (CW) toxicities during an extended follow-up of over 10 years. We report an unusual case of a bone tumor-like CW mass lesion with pathological rib fractures observed 13 years after SBRT for peripheral lung cancer. Despite the initial suspicion of radiation-induced sarcoma, a subsequent incisional biopsy revealed no evidence of malignancy, and a definitive diagnosis of osteonecrosis was made. Thus, long-term observation of over 10 years is required to identify late chronic complications following SBRT.

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来源期刊
Thoracic Cancer
Thoracic Cancer ONCOLOGY-RESPIRATORY SYSTEM
CiteScore
5.20
自引率
3.40%
发文量
439
审稿时长
2 months
期刊介绍: Thoracic Cancer aims to facilitate international collaboration and exchange of comprehensive and cutting-edge information on basic, translational, and applied clinical research in lung cancer, esophageal cancer, mediastinal cancer, breast cancer and other thoracic malignancies. Prevention, treatment and research relevant to Asia-Pacific is a focus area, but submissions from all regions are welcomed. The editors encourage contributions relevant to prevention, general thoracic surgery, medical oncology, radiology, radiation medicine, pathology, basic cancer research, as well as epidemiological and translational studies in thoracic cancer. Thoracic Cancer is the official publication of the Chinese Society of Lung Cancer, International Chinese Society of Thoracic Surgery and is endorsed by the Korean Association for the Study of Lung Cancer and the Hong Kong Cancer Therapy Society. The Journal publishes a range of article types including: Editorials, Invited Reviews, Mini Reviews, Original Articles, Clinical Guidelines, Technological Notes, Imaging in thoracic cancer, Meeting Reports, Case Reports, Letters to the Editor, Commentaries, and Brief Reports.
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