[肿瘤活动性脱髓鞘病变]

Q3 Medicine Brain and Nerve Pub Date : 2024-08-01 DOI:10.11477/mf.1416202712
Yuki Mizumoto, Tetsuya Abe
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引用次数: 0

摘要

肿瘤活动性脱髓鞘病变(TDL)被定义为炎症性脱髓鞘病变,可能在多发性硬化症和相关疾病的治疗过程中出现,也可能是首次脱髓鞘发作,既往病史中没有任何提示脱髓鞘的病史。如果是后者,诊断为脱髓鞘病就非常棘手。特别是在这种情况下,除了神经影像学检查外,通常还需要进行活组织检查,以区分 TDL 与肿瘤或感染性疾病。本文将回顾 TDL 的概念、流行病学、诊断和治疗。
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[Tumefactive Demyelinating Lesions].

Tumefactive demyelinating lesions (TDL), defined as inflammatory demyelinating lesions, may develop either during treatment for multiple sclerosis and related disorders or as the first demyelinating episode without any past medical history suggesting demyelination. If the latter, it would be so delicate to diagnose as demyelination. Especially in such situations, biopsy is often necessary in addition to neuroimaging for distinction TDL with tumorous or infectious diseases. In this article, we will review about concept, epidemiology, diagnosis, and treatment of TDL.

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来源期刊
Brain and Nerve
Brain and Nerve Medicine-Neurology (clinical)
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