Jie Li , Hao Chang , Pengzhe Zhang , Liyu Hou , Wei Li , Yixin Zhang , Zhiqi Lao
{"title":"基于代谢糖工程和二硫化硫的新型肿瘤治疗策略。","authors":"Jie Li , Hao Chang , Pengzhe Zhang , Liyu Hou , Wei Li , Yixin Zhang , Zhiqi Lao","doi":"10.1039/d4ob01027b","DOIUrl":null,"url":null,"abstract":"<div><p>Traditional metabolic glycoengineering involves participation of a monofunctional unnatural monosaccharide. To broaden the application boundary of this powerful technique, a bifunctional molecule, Ac<sub>4</sub>ManNSSN<sub>3</sub>, is designed and applied for a tumor theranostic strategy in this work. The results from both cell and animal experiments show good <em>in situ</em> tumor detection and tumor inhibition effects.</p></div>","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A novel tumor theranostic strategy based on metabolic glycoengineering and disulfidptosis†‡\",\"authors\":\"Jie Li , Hao Chang , Pengzhe Zhang , Liyu Hou , Wei Li , Yixin Zhang , Zhiqi Lao\",\"doi\":\"10.1039/d4ob01027b\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Traditional metabolic glycoengineering involves participation of a monofunctional unnatural monosaccharide. To broaden the application boundary of this powerful technique, a bifunctional molecule, Ac<sub>4</sub>ManNSSN<sub>3</sub>, is designed and applied for a tumor theranostic strategy in this work. The results from both cell and animal experiments show good <em>in situ</em> tumor detection and tumor inhibition effects.</p></div>\",\"PeriodicalId\":2,\"journal\":{\"name\":\"ACS Applied Bio Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2024-08-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Bio Materials\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S1477052024006955\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1477052024006955","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
A novel tumor theranostic strategy based on metabolic glycoengineering and disulfidptosis†‡
Traditional metabolic glycoengineering involves participation of a monofunctional unnatural monosaccharide. To broaden the application boundary of this powerful technique, a bifunctional molecule, Ac4ManNSSN3, is designed and applied for a tumor theranostic strategy in this work. The results from both cell and animal experiments show good in situ tumor detection and tumor inhibition effects.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
