药用大麻使用问题的概念化:简短筛查问卷的开发和初步验证。

IF 3.7 2区 医学 Q1 PSYCHOLOGY, CLINICAL Addictive behaviors Pub Date : 2024-08-10 DOI:10.1016/j.addbeh.2024.108122
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引用次数: 0

摘要

在全球范围内,使用医用大麻(Medicinal Cannabis,MC)治疗慢性疼痛的情况日益增多,但对有问题的 MC 使用的定义仍不明确。在医疗和非医疗背景下,对有问题使用大麻的定义可能存在本质区别,因为被处方 MC 的人通常会产生生理依赖,但这并不一定意味着病态。我们的目标是将有问题地使用 MC 概念化,并编制一份简短的调查问卷,用于识别和量化有问题地使用 MC 的情况。内容验证采用了问题药物使用的广义定义,从不同来源改编并编制了一份包含 36 个项目的初步清单:(a) 用于评估有问题的处方阿片类药物使用情况的筛查工具;(b) 用于评估有问题的娱乐性大麻使用情况的筛查工具;(c) 对 MC 患者的定性访谈。390 名持有管委会卡的美国自认慢性疼痛患者对初始列表中的每个项目进行了 5 点频率评分,并填写了评估各种临床结果的调查问卷。在对初始项目进行滴定后,采用多组测量不变量比较策略,使用两个外部指标:与酒精相关的问题和抑郁,得出了最终的八项目列表,该列表符合基线模型的拟合质量,具有极佳的内部一致性可靠性(α = 0.929),并与焦虑和低生活质量显著相关。最终列表中的项目主要与使用 MC 的负面影响有关。有问题地使用 MC 在生理、社会、情感和功能方面都会产生负面影响。最终的八项目表被命名为 "药用大麻负面后果量表(MCNCS)",该量表是对有问题使用大麻的简短测量,具有初步的信度和效度,可为临床医生和研究人员提供帮助。
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Conceptualizing problematic use of medicinal Cannabis: Development and preliminary validation of a brief screening questionnaire

The use of Medicinal Cannabis (MC) for treating chronic pain is increasing, globally, yet the definition of problematic MC use remains unclear. Defining problematic use of cannabis in medical and non-medical contexts may be fundamentally different since individuals prescribed MC often experience physical dependence, which do not necessarily imply pathology. We aimed to conceptualize problematic use of MC and develop a brief questionnaire for identifying and quantifying problematic MC use. Content validation used a broad definition of problematic substance use, adapting and compiling an initial list of 36 items from various sources: (a) screening tools for assessing problematic prescription opioid medication use; (b) screening tools for problematic recreational cannabis use and (c) qualitative interviews with MC patients. 390 American self-identified chronic pain patients holding a MC card rated each item from the initial list on a 5-point frequency scale and filled out questionnaires assessing various clinical outcomes. Following initial item titration, a multi‐group measurement invariance comparison strategy, using two external indicators: alcohol-related problems and depression, resulted a final eight-item list that met fit quality in a baseline model, presented excellent internal consistency reliability (α = 0.929), and significantly correlated with anxiety and low quality of life. Items in the final list related predominantly to negative consequences of MC use. Problematic use of MC is characterized by negative physiological, social, emotional and functional consequences. The final eight-item list was named the Medicinal Cannabis Negative Consequences Scale (MCNCS), emerging as a brief measure for problematic MC use and demonstrating preliminary reliability and validity, which could aid clinicians and researchers.

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来源期刊
Addictive behaviors
Addictive behaviors 医学-药物滥用
CiteScore
8.40
自引率
4.50%
发文量
283
审稿时长
46 days
期刊介绍: Addictive Behaviors is an international peer-reviewed journal publishing high quality human research on addictive behaviors and disorders since 1975. The journal accepts submissions of full-length papers and short communications on substance-related addictions such as the abuse of alcohol, drugs and nicotine, and behavioral addictions involving gambling and technology. We primarily publish behavioral and psychosocial research but our articles span the fields of psychology, sociology, psychiatry, epidemiology, social policy, medicine, pharmacology and neuroscience. While theoretical orientations are diverse, the emphasis of the journal is primarily empirical. That is, sound experimental design combined with valid, reliable assessment and evaluation procedures are a requisite for acceptance. However, innovative and empirically oriented case studies that might encourage new lines of inquiry are accepted as well. Studies that clearly contribute to current knowledge of etiology, prevention, social policy or treatment are given priority. Scholarly commentaries on topical issues, systematic reviews, and mini reviews are encouraged. We especially welcome multimedia papers that incorporate video or audio components to better display methodology or findings. Studies can also be submitted to Addictive Behaviors? companion title, the open access journal Addictive Behaviors Reports, which has a particular interest in ''non-traditional'', innovative and empirically-oriented research such as negative/null data papers, replication studies, case reports on novel treatments, and cross-cultural research.
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