C. Valach, Emiel F. M. Wouters, A. Ofenheimer, P. Pompilio, Alessandro Gobbi, M. Breyer, Sylvia Hartl, C. Veneroni, T. Mraz, C. Schiffers, O. C. Burghuber, Ahmad Karimi, Christoph Gross, Charles G. Irvin, R. Breyer-Kohansal
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引用次数: 0
摘要
本研究旨在使用 Resmon PRO FULL 设备为儿童和青少年创建特定性别的示波测量参考值。研究对象包括奥地利 LEAD 普通人群中 6 至 17 岁的健康参与者(981 人)。受试者体重正常(体重指数≤第 99 百分位数),肺活量正常(总肺活量≥正常值下限)。振荡测量数据采用 8 赫兹的单频模式采集。采用 LMS(lambda、mu、sigma)方法为总肺活量(tot)、吸气肺活量(insp)和呼气肺活量(exp)的阻力(R)和电抗(X)以及阻抗模量(Z)值建立了性别特异性预测方程。所有振荡测量参数的参考方程都是为 6 至 17 岁的白种儿童创建的,这些儿童的身高跨度为 101 厘米至 183 厘米,肺活量跨度为 1.7 升至 8.8 升 TLC。随着身高的增加,R 值和 Z 值逐渐减小,X 值逐渐增大。振荡参数与肺活量的曲线不同于与身高的曲线。我们的研究采用严格定义的体重和肺活量标准,为儿童和青少年的示波测量参数提供了参考值。我们的研究采用严格定义的体重和肺活量标准,为儿童和青少年提供了振荡测量参数的参考值。根据身高或肺活量校正后,没有发现振荡测量参数存在性别差异。
Oscillometry Reference Values for Children and Adolescents
Oscillometry devices allow quantification of respiratory function at tidal breathing but device-specific reference equations are scarce: the present study aims to create sex-specific oscillometric reference values for children and adolescents using the Resmon PRO FULL device.Healthy participants (N=981) aged 6 to 17 years of the Austrian LEAD general population cohort were included. Subjects had normal weight (BMI≤99th percentile) and normal lung volumes (total lung capacity (TLC)≥lower limit of normal). Oscillometry data were collected using a single frequency mode of 8 Hz. Sex-specific prediction equations were developed for total (tot), inspiratory (insp) and expiratory (exp) resistance (R) and reactance (X) as well as for the modulus of impedance (Z) value using the LMS (lambda, mu, sigma) method. Height was used as a single covariate.Reference equations for all oscillometry parameters were created for Caucasian children aged 6 to 17 years with a height span from 101 to 183 cm and a lung volume span from 1.7 L to 8.8 L TLC. R and Z values progressively decrease and X values increase with increasing height. Oscillometry parametersversuslung volume curves differ from thoseversusheight curves. Stratified for lung size, no sex differences are found for oscillometry parameters.Our study provides reference values for oscillometry parameters in children and adolescents using strictly defined criteria for weight and lung volumes. No sex related differences in oscillometry parameters corrected for height or lung size are found.
期刊介绍:
ERJ Open Research is a fully open access original research journal, published online by the European Respiratory Society. The journal aims to publish high-quality work in all fields of respiratory science and medicine, covering basic science, clinical translational science and clinical medicine. The journal was created to help fulfil the ERS objective to disseminate scientific and educational material to its members and to the medical community, but also to provide researchers with an affordable open access specialty journal in which to publish their work.