MUC2 表达调节结直肠癌中的免疫渗透

Christophe M. Raynaud, Ayesha Jabeen, Eiman I. Ahmed, Satanay Hubrack, Apryl Sanchez, Shimaa Sherif, Ahmad A Al-Shaibi, Jessica Roelands, Bernice Lo, Davide Bedognetti, Wouter Hendrickx
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引用次数: 0

摘要

导言 大肠癌(CRC)是一种普遍存在的恶性肿瘤,在全球范围内发病率和死亡率都很高。深入了解癌细胞与肿瘤微环境中其他细胞的相互作用对于制定有效的治疗策略至关重要。MUC2是胃肠道粘液保护层的主要成分,它与癌症进展和免疫反应调节有关。
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MUC2 Expression Modulates Immune Infiltration in Colorectal Cancer
Introduction Colorectal cancer (CRC) is a prevalent malignancy with significant morbidity and mortality worldwide. A deeper understanding of the interaction of cancer cells with other cells in the tumor microenvironment is crucial for devising effective therapeutic strategies. MUC2, a major component of the protective mucus layer in the gastrointestinal tract, has been implicated in CRC progression and immune response regulation.
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