Andrea Iglesias Ramas, Samuele Pio Lipani, Rosalind J. Allen
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Population genetics: an introduction for physicists
Population genetics lies at the heart of evolutionary theory. This topic
forms part of many biological science curricula but is rarely taught to physics
students. Since physicists are becoming increasingly interested in biological
evolution, we aim to provide a brief introduction to population genetics,
written for physicists. We start with two background chapters: chapter 1
provides a brief historical introduction to the topic, while chapter 2 provides
some essential biological background. We begin our main content with chapter 3
which discusses the key concepts behind Darwinian natural selection and
Mendelian inheritance. Chapter 4 covers the basics of how variation is
maintained in populations, while chapter 5 discusses mutation and selection. In
chapter 6 we discuss stochastic effects in population genetics using the
Wright-Fisher model as our example, and finally we offer concluding thoughts
and references to excellent textbooks in chapter 7.