{"title":"用于大视场神经活动双色成像的轻型微型内窥镜","authors":"","doi":"10.1016/j.rio.2024.100732","DOIUrl":null,"url":null,"abstract":"<div><p>We present the design and the experimental characterization of a miniature “portable” mini-endoscope with a large field-of-view (<span><math><mrow><mo>≈</mo><mn>360</mn><mspace></mspace><mi>r</mi><mi>m</mi><mi>m</mi><mi>u</mi><mi>m</mi></mrow></math></span>) that operates with two spectral bands adapted for mCherry (peak emission at 610 nm) and GCaMP6s (peak emission at 513 nm) fluorophores. The diameter of the implant is very small (0.5 mm), the total weight is 1.8 g, the size is <span><math><mrow><mn>10</mn><mo>×</mo><mn>12</mn><mo>×</mo><mn>21</mn><mspace></mspace><msup><mrow><mi>mm</mi></mrow><mrow><mn>3</mn></mrow></msup></mrow></math></span>, and the lateral resolution of the device is <span><math><mrow><mo>≈</mo><mn>4</mn><mo>.</mo><mn>5</mn><mspace></mspace><mi>μ</mi><mi>m</mi></mrow></math></span>. This compact and lightweight system allows investigation of the neural activity of two different neuronal populations.</p></div>","PeriodicalId":21151,"journal":{"name":"Results in Optics","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666950124001299/pdfft?md5=dfd8bef8682797d20f316116ac4d415a&pid=1-s2.0-S2666950124001299-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Lightweight mini-endoscope for two color imaging of neural activities with large field of view\",\"authors\":\"\",\"doi\":\"10.1016/j.rio.2024.100732\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>We present the design and the experimental characterization of a miniature “portable” mini-endoscope with a large field-of-view (<span><math><mrow><mo>≈</mo><mn>360</mn><mspace></mspace><mi>r</mi><mi>m</mi><mi>m</mi><mi>u</mi><mi>m</mi></mrow></math></span>) that operates with two spectral bands adapted for mCherry (peak emission at 610 nm) and GCaMP6s (peak emission at 513 nm) fluorophores. The diameter of the implant is very small (0.5 mm), the total weight is 1.8 g, the size is <span><math><mrow><mn>10</mn><mo>×</mo><mn>12</mn><mo>×</mo><mn>21</mn><mspace></mspace><msup><mrow><mi>mm</mi></mrow><mrow><mn>3</mn></mrow></msup></mrow></math></span>, and the lateral resolution of the device is <span><math><mrow><mo>≈</mo><mn>4</mn><mo>.</mo><mn>5</mn><mspace></mspace><mi>μ</mi><mi>m</mi></mrow></math></span>. This compact and lightweight system allows investigation of the neural activity of two different neuronal populations.</p></div>\",\"PeriodicalId\":21151,\"journal\":{\"name\":\"Results in Optics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2666950124001299/pdfft?md5=dfd8bef8682797d20f316116ac4d415a&pid=1-s2.0-S2666950124001299-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Results in Optics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666950124001299\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Physics and Astronomy\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Results in Optics","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666950124001299","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Physics and Astronomy","Score":null,"Total":0}
Lightweight mini-endoscope for two color imaging of neural activities with large field of view
We present the design and the experimental characterization of a miniature “portable” mini-endoscope with a large field-of-view () that operates with two spectral bands adapted for mCherry (peak emission at 610 nm) and GCaMP6s (peak emission at 513 nm) fluorophores. The diameter of the implant is very small (0.5 mm), the total weight is 1.8 g, the size is , and the lateral resolution of the device is . This compact and lightweight system allows investigation of the neural activity of two different neuronal populations.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
