{"title":"吃出抗生素","authors":"Felix Wong","doi":"10.1038/s41589-024-01698-y","DOIUrl":null,"url":null,"abstract":"Understanding the physiological effects of antibiotics on bacterial cells is important for informing antibiotic use. Bacterial communities treated with antibiotics in a microfluidic device maintain glucose consumption at the community periphery, protecting interior cells from the effects of antibiotics.","PeriodicalId":18832,"journal":{"name":"Nature chemical biology","volume":"51 1","pages":""},"PeriodicalIF":12.9000,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Eating a way out of antibiotics\",\"authors\":\"Felix Wong\",\"doi\":\"10.1038/s41589-024-01698-y\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Understanding the physiological effects of antibiotics on bacterial cells is important for informing antibiotic use. Bacterial communities treated with antibiotics in a microfluidic device maintain glucose consumption at the community periphery, protecting interior cells from the effects of antibiotics.\",\"PeriodicalId\":18832,\"journal\":{\"name\":\"Nature chemical biology\",\"volume\":\"51 1\",\"pages\":\"\"},\"PeriodicalIF\":12.9000,\"publicationDate\":\"2024-08-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature chemical biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1038/s41589-024-01698-y\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature chemical biology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1038/s41589-024-01698-y","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Understanding the physiological effects of antibiotics on bacterial cells is important for informing antibiotic use. Bacterial communities treated with antibiotics in a microfluidic device maintain glucose consumption at the community periphery, protecting interior cells from the effects of antibiotics.
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Nature Chemical Biology stands as an esteemed international monthly journal, offering a prominent platform for the chemical biology community to showcase top-tier original research and commentary. Operating at the crossroads of chemistry, biology, and related disciplines, chemical biology utilizes scientific ideas and approaches to comprehend and manipulate biological systems with molecular precision.
The journal embraces contributions from the growing community of chemical biologists, encompassing insights from chemists applying principles and tools to biological inquiries and biologists striving to comprehend and control molecular-level biological processes. We prioritize studies unveiling significant conceptual or practical advancements in areas where chemistry and biology intersect, emphasizing basic research, especially those reporting novel chemical or biological tools and offering profound molecular-level insights into underlying biological mechanisms.
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