评估麦克马洪评分对地震所致横纹肌溶解症死亡率的预测作用:一项回顾性研究。

IF 3.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Postgraduate Medical Journal Pub Date : 2024-08-14 DOI:10.1093/postmj/qgae103
Mahmut Yaman, Abdullah Şen, Hasan Mansur Durgun, Eren Eynel, Sema Belek, Şilan Göger Ülgüt, Murat Orak, Cahfer Güloğlu
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引用次数: 0

摘要

背景:在地震等自然灾害中,建筑物倒塌会压住人,导致挤压综合征和横纹肌溶解症。这种危及生命的情况通常会导致急性肾损伤。我们旨在确定麦克马洪评分在预测地震患者因横纹肌溶解症导致的死亡率方面的有效性:这是一项回顾性观察研究。本研究分析了因地震到急诊科就诊的患者的临床和实验室数据。通过评估肌酸激酶、血清肌酐水平、年龄和性别等因素,计算出麦克马洪评分:研究共纳入 151 名患者,其中男性 74 人(49.0%),女性 77 人(51.0%)。在单变量模型中,观察到麦克马洪评分和急性肾损伤风险在区分有死亡和无死亡患者方面有显著效果(P < .05)。在麦克马洪评分截止值为 6 时,也观察到了明显的有效性,曲线下面积为 0.723。在此临界值下,灵敏度为 80.0%,特异度为 64.5%:结论:在急诊医学和灾难管理中使用麦克马洪评分在快速决策过程中起着至关重要的作用,因为它能有效预测死亡率。
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Evaluating the McMahon score for predicting mortality in earthquake-induced rhabdomyolysis: a retrospective study.

Background: In natural disasters like earthquakes, building collapses can trap individuals, causing crush syndrome and rhabdomyolysis. This life-threatening condition often leads to acute kidney injury. We aimed to determine the effectiveness of the McMahon score in predicting mortality due to rhabdomyolysis in patients affected by the earthquake.

Methods: This is a retrospective observational study. In this study, the clinical and laboratory data of patients who presented to the emergency department due to the earthquake were analyzed. The McMahon score was calculated by evaluating factors such as creatine kinase, serum creatinine levels, age, and gender.

Results: The study included 151 patients, of whom 74 (49.0%) were male and 77 (51.0%) were female. In the univariate model, significant (P < .05) effectiveness was observed in differentiating between patients with and without mortality for McMahon score and the risk of acute kidney injury. At a McMahon score cutoff of 6, significant effectiveness was also observed, with an area under the curve of 0.723. At this cutoff value, the sensitivity was 80.0% and the specificity was 64.5%.

Conclusions: The use of the McMahon score in emergency medicine and disaster management plays a crucial role in rapid decision-making processes due to its effectiveness in predicting mortality.

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来源期刊
Postgraduate Medical Journal
Postgraduate Medical Journal 医学-医学:内科
CiteScore
8.50
自引率
2.00%
发文量
131
审稿时长
2.5 months
期刊介绍: Postgraduate Medical Journal is a peer reviewed journal published on behalf of the Fellowship of Postgraduate Medicine. The journal aims to support junior doctors and their teachers and contribute to the continuing professional development of all doctors by publishing papers on a wide range of topics relevant to the practicing clinician and teacher. Papers published in PMJ include those that focus on core competencies; that describe current practice and new developments in all branches of medicine; that describe relevance and impact of translational research on clinical practice; that provide background relevant to examinations; and papers on medical education and medical education research. PMJ supports CPD by providing the opportunity for doctors to publish many types of articles including original clinical research; reviews; quality improvement reports; editorials, and correspondence on clinical matters.
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