单导联远程健康心电图信号中的 QRS 检测:开源算法基准测试。

PLOS digital health Pub Date : 2024-08-13 eCollection Date: 2024-08-01 DOI:10.1371/journal.pdig.0000538
Florian Kristof, Maximilian Kapsecker, Leon Nissen, James Brimicombe, Martin R Cowie, Zixuan Ding, Andrew Dymond, Stephan M Jonas, Hannah Clair Lindén, Gregory Y H Lip, Kate Williams, Jonathan Mant, Peter H Charlton
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引用次数: 0

摘要

背景和目的:心电图(ECG)分析的一个关键步骤是检测 QRS 波群,尤其是在检测心律失常时。由于远程医疗心电图比传统临床心电图噪音更大,因此给自动分析带来了新的挑战。本研究的目的是确定用于远程健康心电图的性能最佳的开源 QRS 检测器:方法:在六个数据集上评估了 18 个开源 QRS 检测器的性能。这些数据集包括四个在监护下采集的心电图数据集和两个在无临床监护下采集的远程健康心电图数据集。远程健康心电图由双手间记录的单导联心电图组成,其中包括在筛查心房颤动(AF)的 SAFER 研究中收集的 479 份心电图的新数据集。对照人工标注对性能进行了评估:结果:共有 12 个 QRS 检测器在临床监督下采集的心电图上表现良好(F1 分数≥0.96)。然而,在远程医疗心电图上表现良好的较少:5 个在 TELE 心电图数据库上表现良好;6 个在高质量的 SAFER 数据上表现良好;在低质量的 SAFER 数据上表现较差(3 个 QRS 检测器的 F1 为 0.78-0.84)。房颤的存在对性能影响不大:结论:Neurokit 和新南威尔士大学的 QRS 检测器在本研究中表现最佳。它们在高质量远程健康心电图上的表现足够好,但在低质量心电图上的表现却不尽人意。这表明有必要适当处理低质量心电图,以确保只有能够准确分析的心电图才能用于临床决策。
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QRS detection in single-lead, telehealth electrocardiogram signals: Benchmarking open-source algorithms.

Background and objectives: A key step in electrocardiogram (ECG) analysis is the detection of QRS complexes, particularly for arrhythmia detection. Telehealth ECGs present a new challenge for automated analysis as they are noisier than traditional clinical ECGs. The aim of this study was to identify the best-performing open-source QRS detector for use with telehealth ECGs.

Methods: The performance of 18 open-source QRS detectors was assessed on six datasets. These included four datasets of ECGs collected under supervision, and two datasets of telehealth ECGs collected without clinical supervision. The telehealth ECGs, consisting of single-lead ECGs recorded between the hands, included a novel dataset of 479 ECGs collected in the SAFER study of screening for atrial fibrillation (AF). Performance was assessed against manual annotations.

Results: A total of 12 QRS detectors performed well on ECGs collected under clinical supervision (F1 score ≥0.96). However, fewer performed well on telehealth ECGs: five performed well on the TELE ECG Database; six performed well on high-quality SAFER data; and performance was poorer on low-quality SAFER data (three QRS detectors achieved F1 of 0.78-0.84). The presence of AF had little impact on performance.

Conclusions: The Neurokit and University of New South Wales QRS detectors performed best in this study. These performed sufficiently well on high-quality telehealth ECGs, but not on low-quality ECGs. This demonstrates the need to handle low-quality ECGs appropriately to ensure only ECGs which can be accurately analysed are used for clinical decision making.

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