针对多种适应症长期使用食管支架的安全性。

IF 2.1 3区 医学 Q3 RESPIRATORY SYSTEM Journal of thoracic disease Pub Date : 2024-07-30 Epub Date: 2024-07-25 DOI:10.21037/jtd-24-366
Bryce M Bludevich, Benjamin A Palleiko, Hayley Reddington, Maria Navarro, S Alyssa Q Uy, Mark W Maxfield, Isabel Emmerick, Feiran Lou, Karl Fabian L Uy
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引用次数: 0

摘要

背景:长期(>30 天)食管支架植入术存在争议。以往的研究记录了与长期使用食管支架相关的并发症。本研究旨在调查与长期使用食管支架相关的并发症:方法:对 2010-2020 年间胸外科因任何原因进行的支架植入术进行回顾性研究。如果患者在首次支架置入后接受了至少 30 天的随访,则将其纳入研究范围。结果包括支架停留时间、患者预后、手术和支架相关并发症:共纳入 56 例患者,其中 25 例患者放置了≥2 个支架;共放置了 90 个支架。初始食管支架停留时间的中位数为59天[四分位间距(IQR),21-119]。支架移位是最常见的并发症,良性适应症的发生率更高(P=0.12)。随着停留时间的延长,任何并发症的发生率都在下降。短期内的并发症发生率(结论:在 10 年的时间里,没有发生支架侵蚀主动脉或食管穿孔的情况,最常见的支架相关并发症是支架移位。在我们的队列中,长期食管支架置入术并未导致支架相关并发症发生率增加。该系列病例表明,长期支架可安全用于多种不同适应症。可能需要进行随机对照研究来验证这些发现。
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Safety of long-term esophageal stent use for multiple indications.

Background: Long-term (>30 days) esophageal stenting is controversial. Previous studies have documented complications associated with long-term esophageal stent use. This study's objective was to investigate complications associated with long-term esophageal stent use.

Methods: A retrospective review of stenting done by thoracic surgery for any reason between 2010-2020 was completed. Patients were included if they had at least 30 days of follow-up after their initial stent placement. Outcomes included stent dwell time, patient outcomes, procedural and stent-related complications.

Results: Fifty-six patients, with 25 having ≥2 stents placed were included; overall, 90 stents were placed. The median length of initial esophageal stent dwell time was 59 [interquartile range (IQR), 21-119] days. Stent migration was the most common complication and occurred more with benign indications (P=0.12). As the length of dwell time increased, prevalence of any complication decreased. Complication rates between short-term (<30 days) and long-term stents were not significantly different (P=0.39). No instances of esophageal perforation or aortoesophageal fistulas related to stents were identified. There was one instance of post-esophagectomy tracheoesophageal fistula which was managed successfully with prolonged stenting.

Conclusions: Over a 10-year period, there were no instances of stent erosion into the aorta or esophageal perforation, and the most frequent stent-related complication was stent migration. Long-term esophageal stenting did not result in increased rates of stent related complications in our cohort. This case series demonstrates that long-term stents may be safely used for many different indications. Randomized controlled studies may be needed to validate these findings.

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来源期刊
Journal of thoracic disease
Journal of thoracic disease RESPIRATORY SYSTEM-
CiteScore
4.60
自引率
4.00%
发文量
254
期刊介绍: The Journal of Thoracic Disease (JTD, J Thorac Dis, pISSN: 2072-1439; eISSN: 2077-6624) was founded in Dec 2009, and indexed in PubMed in Dec 2011 and Science Citation Index SCI in Feb 2013. It is published quarterly (Dec 2009- Dec 2011), bimonthly (Jan 2012 - Dec 2013), monthly (Jan. 2014-) and openly distributed worldwide. JTD received its impact factor of 2.365 for the year 2016. JTD publishes manuscripts that describe new findings and provide current, practical information on the diagnosis and treatment of conditions related to thoracic disease. All the submission and reviewing are conducted electronically so that rapid review is assured.
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