{"title":"用于医疗应用的 Cr -51 生成反应的理论模型验证","authors":"","doi":"10.1016/j.anucene.2024.110853","DOIUrl":null,"url":null,"abstract":"<div><p>This study provides a thorough simulation and analysis of cross-sections for the production of <sup>51</sup>Cr by various nuclear reactions. Our objective is to validate the production process of <sup>51</sup>Cr, an essential radionuclide used in nuclear medicine for studying blood cells’ physiological and pathological characteristics. In order to do this, we used the nuclear level density, optical model potential, and preequilibrium model integrated into the TALYS 1.96 code for theoretical modeling. The obtained results have been compared with experimental data taken from the EXFOR database. We have also taken TENDL library data and TALYS as a whole code to enhance our evaluation. The study assesses multiple nuclear reactions: <sup>51</sup>V(p,n)<sup>51</sup>Cr, <sup>51</sup>V(d,2n)<sup>51</sup>Cr, <sup>48</sup>Ti(a,n)<sup>51</sup>Cr, <sup>52</sup>Cr(n,2n)<sup>51</sup>Cr, <sup>54</sup>Fe(n,a)<sup>51</sup>Cr, and <sup>55</sup>Mn(p,x)<sup>51</sup>Cr in order to identify the most effective routes in terms of production, relative variance analysis, presence of nuclidic impurities, and the optimum energy range. The cross-section, theoretical yield, target thickness, and activity have been calculated to optimize and help in finding the best reaction conditions, which improve the production of <sup>51</sup>Cr inside a cyclotron for medical uses.</p></div>","PeriodicalId":8006,"journal":{"name":"Annals of Nuclear Energy","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Theoretical models validation of Cr -51 production reactions for medical applications\",\"authors\":\"\",\"doi\":\"10.1016/j.anucene.2024.110853\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>This study provides a thorough simulation and analysis of cross-sections for the production of <sup>51</sup>Cr by various nuclear reactions. Our objective is to validate the production process of <sup>51</sup>Cr, an essential radionuclide used in nuclear medicine for studying blood cells’ physiological and pathological characteristics. In order to do this, we used the nuclear level density, optical model potential, and preequilibrium model integrated into the TALYS 1.96 code for theoretical modeling. The obtained results have been compared with experimental data taken from the EXFOR database. We have also taken TENDL library data and TALYS as a whole code to enhance our evaluation. The study assesses multiple nuclear reactions: <sup>51</sup>V(p,n)<sup>51</sup>Cr, <sup>51</sup>V(d,2n)<sup>51</sup>Cr, <sup>48</sup>Ti(a,n)<sup>51</sup>Cr, <sup>52</sup>Cr(n,2n)<sup>51</sup>Cr, <sup>54</sup>Fe(n,a)<sup>51</sup>Cr, and <sup>55</sup>Mn(p,x)<sup>51</sup>Cr in order to identify the most effective routes in terms of production, relative variance analysis, presence of nuclidic impurities, and the optimum energy range. The cross-section, theoretical yield, target thickness, and activity have been calculated to optimize and help in finding the best reaction conditions, which improve the production of <sup>51</sup>Cr inside a cyclotron for medical uses.</p></div>\",\"PeriodicalId\":8006,\"journal\":{\"name\":\"Annals of Nuclear Energy\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-08-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Nuclear Energy\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0306454924005164\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"NUCLEAR SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Nuclear Energy","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0306454924005164","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NUCLEAR SCIENCE & TECHNOLOGY","Score":null,"Total":0}
Theoretical models validation of Cr -51 production reactions for medical applications
This study provides a thorough simulation and analysis of cross-sections for the production of 51Cr by various nuclear reactions. Our objective is to validate the production process of 51Cr, an essential radionuclide used in nuclear medicine for studying blood cells’ physiological and pathological characteristics. In order to do this, we used the nuclear level density, optical model potential, and preequilibrium model integrated into the TALYS 1.96 code for theoretical modeling. The obtained results have been compared with experimental data taken from the EXFOR database. We have also taken TENDL library data and TALYS as a whole code to enhance our evaluation. The study assesses multiple nuclear reactions: 51V(p,n)51Cr, 51V(d,2n)51Cr, 48Ti(a,n)51Cr, 52Cr(n,2n)51Cr, 54Fe(n,a)51Cr, and 55Mn(p,x)51Cr in order to identify the most effective routes in terms of production, relative variance analysis, presence of nuclidic impurities, and the optimum energy range. The cross-section, theoretical yield, target thickness, and activity have been calculated to optimize and help in finding the best reaction conditions, which improve the production of 51Cr inside a cyclotron for medical uses.
期刊介绍:
Annals of Nuclear Energy provides an international medium for the communication of original research, ideas and developments in all areas of the field of nuclear energy science and technology. Its scope embraces nuclear fuel reserves, fuel cycles and cost, materials, processing, system and component technology (fission only), design and optimization, direct conversion of nuclear energy sources, environmental control, reactor physics, heat transfer and fluid dynamics, structural analysis, fuel management, future developments, nuclear fuel and safety, nuclear aerosol, neutron physics, computer technology (both software and hardware), risk assessment, radioactive waste disposal and reactor thermal hydraulics. Papers submitted to Annals need to demonstrate a clear link to nuclear power generation/nuclear engineering. Papers which deal with pure nuclear physics, pure health physics, imaging, or attenuation and shielding properties of concretes and various geological materials are not within the scope of the journal. Also, papers that deal with policy or economics are not within the scope of the journal.