Jeyaseelan Augustine, Aadithya B Urs, Kuldeep Singh, Sunita Gupta
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引用次数: 0
摘要
神经瘤又称许旺瘤,是一种良性、生长缓慢的包裹性肿瘤,由周围神经纤维鞘的许旺细胞产生。虽然这种肿瘤极为罕见,但约有 25%-45% 的病例会影响头颈部。在口腔内部,舌头是最常见的部位,很少累及前庭粘膜。在此,我们报告了一例罕见的前庭粘膜许旺瘤病例,患者是一名 13 岁的女孩,并对现有文献进行了综述。临床上,根据年龄、部位和外观,诊断为良性肿瘤,如脂肪瘤、纤维瘤、神经纤维瘤和唾液腺良性病变。切除活检结果显示,患者体内只有安东尼 A 型组织,中央有嗜酸性韦罗凯体,周围是纺锤形的神经瘤细胞,排列紧密,核呈波浪状扭曲排列。患者 6 个月后未再复发。因此,本病例在年龄、发病部位和组织病理学(安东尼 A 型神经瘤)等方面均属罕见,因此对推测的初步诊断具有重要意义。在此,我们还对早期诊断病例的生长模式类型进行了假设。
Vestibular Schwannoma in a paediatric case-A rare entity.
Neurilemmoma, also known as Schwannoma, is a benign, slow-growing, encapsulated neoplasm that arises from Schwann cells of the peripheral nerve sheath. Although it is extremely rare, it affects the head and neck region in roughly 25-45% of all cases. Intraorally, the tongue is the most common site and is rarely involves vestibular mucosa. Here, we report a rare case of Schwannoma of vestibular mucosa in a 13-year-old girl and contribute a review to the current literature. Clinically, based on age, site, and appearance, a diagnosis of a benign tumour such as lipoma, fibroma, neurofibroma, and benign lesions of salivary glands was made. An excisional biopsy showed solely Antoni type A tissue with central acellular eosinophilic Verocay bodies surrounded by spindle-shaped neurilemma cells arranged compactly with wavy, twisted nuclei arranged in a palisaded manner. The patient was recurrence-free after 6 months. Hence, this case is of interest due to its rarity in terms of age, site, and histopathology (Antoni type A neurilemmoma) for a presumed initial diagnosis. Here, we also hypothesize regarding the type of growth pattern in the earlier diagnosed cases.
期刊介绍:
The journal of Oral and Maxillofacial Pathology [ISSN:print-(0973-029X, online-1998-393X)] is a tri-annual journal published on behalf of “The Indian Association of Oral and Maxillofacial Pathologists” (IAOMP). The publication of JOMFP was started in the year 1993. The journal publishes papers on a wide spectrum of topics associated with the scope of Oral and Maxillofacial Pathology, also, ensuring scientific merit and quality. It is a comprehensive reading material for the professionals who want to upgrade their diagnostic skills in Oral Diseases; allows exposure to newer topics and methods of research in the Oral-facial Tissues and Pathology. New features allow an open minded thinking and approach to various pathologies. It also encourages authors to showcase quality work done by them and to compile relevant cases which are diagnostically challenging. The Journal takes pride in maintaining the quality of articles and photomicrographs.