改良的体外肾脏重建以促进胸腹主动脉瘤的栅栏-分支血管内修复术

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-08-18 DOI:10.1177/15266028241270690
Jack Stutz, Guilherme Baumgardt Barbosa Lima, Ying Huang, Bernado C Mendes, Thanila A Macedo, Gustavo S Oderich
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引用次数: 0

摘要

目的:报告在一名有2个小的右RA(RRA)的患者身上使用改良的体外肾动脉(RA)重建术,以备计划中的胸腹主动脉瘤(TAAA)开孔-分支血管内主动脉修复术(FB-EVAR):对一名累及腹腔轴(CA)、肠系膜上动脉(SMA)、单个左侧RA(LRA)和2个小动脉瘤的II度TAAA患者采用了分期杂交修复术:使用辅助杂交手术可优化或促进 FB-EVAR。在该患者中,抢救 2 个小 RA 并不非常适合分支支架植入术,但通过改良的体外 RA 重建,在保留肾脏实质和功能的前提下,抢救 2 个小 RA 是可行的:本病例报告展示了一种混合方法,该方法克服了血管内肾动脉全切术最常见的局限性之一,即直径小、早期分叉和多血管。经过改良的体外移植技术可以进行细致的肾动脉重建,而不会受到热缺血的有害影响,也不会像传统的台上体外自体移植那样需要繁琐地重建输尿管和静脉。该技术仅用于少数病例,但会增加开放式手术的发病率。病例选择至关重要。
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Modified Ex Vivo Renal Reconstruction to Facilitate Fenestrated-Branched Endovascular Repair of a Thoracoabdominal Aortic Aneurysm.

Purpose: To report the use of modified ex vivo renal artery (RA) reconstruction in a patient with 2 small right RAs (RRAs) in anticipation of planned fenestrated-branched endovascular aortic repair (FB-EVAR) of thoracoabdominal aortic aneurysm (TAAA).

Case report: A staged hybrid repair was utilized in a patient with Extent II TAAA involving celiac axis (CA), superior mesenteric artery (SMA), single left RA (LRA), and 2 small (<3 mm) RRAs. The first-stage operation consisted of hepato-renal bypass using modified ex vivo renal reconstruction with single end-to-end anastomosis to both RAs using a saphenous vein graft. A second stage FB-EVAR was performed using patient-specific manufactured stent-graft with 3 fenestrations for the CA, SMA, and LRA 6 weeks later. The patient recovered with no complications. At 4 years, the patient had widely patent hepato-renal bypass and target vessels with normal renal function.

Conclusion: The use of adjunctive hybrid procedures may optimize or facilitate FB-EVAR. In this patient, salvage of 2 small RAs was not ideally suited for branch stenting but was possible using modified ex vivo RA reconstruction with preservation of kidney parenchyma and function.

Clinical impact: This case report illustrates a hybrid approach to overcome one of the most frequent limitations to total endovascular incorporation of renal arteries, eg small diameter, early bifurcation and multiple vessels. The modified ex vivo technique allows meticulous renal artery reconstruction without the deleterious effect of warm ischemia and without the cumbersome reconstruction of ureter and vein that is needed with traditional on table ex vivo auto transplantation. The technique is used in a minority of cases and adds the morbidity of open approach. Case selection is of paramount importance.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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