胶质母细胞瘤的浸润边缘：重要的是留下了什么。

IF 10 1区医学 Q1 ONCOLOGY Clinical Cancer Research Pub Date : 2024-11-01 DOI:10.1158/1078-0432.CCR-24-1819

Philipp Karschnia, Joerg-Christian Tonn, Daniel P Cahill

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引用次数: 0

摘要

对于新确诊的胶质母细胞瘤患者来说，超越造影剂增强肿瘤边界的最大限度切除是一种新兴的手术策略。最近的一项研究提供了证据，详细说明了更具侵袭性的手术与其他临床预后指标的交互作用，为手术决策提供了指导，并让临床试验人员了解了对切除范围进行分层的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Infiltrative Margins in Glioblastoma: Important Is What Has Been Left behind.

Supramaximal resection beyond the contrast-enhancing tumor borders represents an emerging surgical strategy for patients with newly diagnosed glioblastoma. A recent study provides evidence detailing the interactive effects of more aggressive surgery on other clinical predictors of outcome, supporting guidance for surgical decision-making and informing clinical trialists about the need to stratify for extent of resection. See related article by Park et al., p. 4866.

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来源期刊

Clinical Cancer Research 医学-肿瘤学

CiteScore

20.10

自引率

1.70%

发文量

1207

审稿时长

2.1 months

期刊介绍： Clinical Cancer Research is a journal focusing on groundbreaking research in cancer, specifically in the areas where the laboratory and the clinic intersect. Our primary interest lies in clinical trials that investigate novel treatments, accompanied by research on pharmacology, molecular alterations, and biomarkers that can predict response or resistance to these treatments. Furthermore, we prioritize laboratory and animal studies that explore new drugs and targeted agents with the potential to advance to clinical trials. We also encourage research on targetable mechanisms of cancer development, progression, and metastasis.