单发性睾丸浆细胞瘤:病例报告。

IF 1.5 4区 医学 Q3 UROLOGY & NEPHROLOGY Urologia Internationalis Pub Date : 2024-08-19 DOI:10.1159/000540967
Masanori Nishimura, Takeshi Nomura, Masahiro Fujimoto, Yoshihito Hiura
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引用次数: 0

摘要

导言:睾丸浆细胞瘤是一种极为罕见的恶性肿瘤,可单独发生,也称为单发睾丸浆细胞瘤(STP),也可与多发性骨髓瘤(MM)同时发生。以往的研究表明,STP 预后良好,可通过放疗(RT)或手术等局部治疗治愈。我们报告了一例播散至肋骨的 STP 病例。患者需要接受全身化疗。病例介绍 一名 69 岁的男性因左侧阴囊肿胀转诊至我院。患者接受了左侧腹股沟高位睾丸切除术。根据病理检查,标本被诊断为睾丸浆细胞瘤。由于 MM 检测呈阴性,患者接受了随访。16 个月后,虽然血清蛋白电泳未显示存在 M 蛋白,但在左侧边缘发现了多发性骨病变。因此,患者接受了 4 个疗程的化疗,至今未发现复发迹象。结论 STP 是一种极其罕见的疾病,这掩盖了它的真实预后。如果 STP 复发,应考虑对患者进行全身化疗,并且有必要进行长期随访以了解疾病的性质。
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Solitary Testicular Plasmacytoma: A Case Report.

Introduction: Plasmacytoma of the testis is an extremely rare malignancy that may occur as a solitary tumor, also known as solitary testicular plasmacytoma (STP), or in conjunction with multiple myeloma (MM). Previous studies have shown that STP has a good prognosis and can be cured with localized treatments like radiotherapy or surgery. We report a case of STP with dissemination to the ribs. The patient required systemic chemotherapy.

Case presentation: A 69-year-old man was referred to our hospital due to swelling of the left scrotum. The patient underwent left inguinal high orchiectomy. Based on pathological examination, the specimen was diagnosed as testicular plasmacytoma. As the tests for MM were negative, the patient was followed up. Sixteen months later, multiple bone lesions were detected in the left rims, although serum protein electrophoresis did not show the presence of M protein. Therefore, the patient received 4 courses of chemotherapy, and no signs of recurrence have been detected so far.

Conclusion: STP is an extremely rare disease, which obscures its true prognosis. Systemic chemotherapy should be considered for patients with STP in case of recurrence, and long-term follow-up is necessary to understand the nature of the disease.

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来源期刊
Urologia Internationalis
Urologia Internationalis 医学-泌尿学与肾脏学
CiteScore
3.30
自引率
6.20%
发文量
94
审稿时长
3-8 weeks
期刊介绍: Concise but fully substantiated international reports of clinically oriented research into science and current management of urogenital disorders form the nucleus of original as well as basic research papers. These are supplemented by up-to-date reviews by international experts on the state-of-the-art of key topics of clinical urological practice. Essential topics receiving regular coverage include the introduction of new techniques and instrumentation as well as the evaluation of new functional tests and diagnostic methods. Special attention is given to advances in surgical techniques and clinical oncology. The regular publication of selected case reports represents the great variation in urological disease and illustrates treatment solutions in singular cases.
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