一名 15 岁女孩的卵巢黏液癌,罕见病例报告和文献综述。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-08-20 DOI:10.5146/tjpath.2024.13496
Hazwa Karathanathodi Hamza, Nausheen Yaqoob, Khadra Ahmed Galaal, Aref Zribi, Ibrahim Al-Haddabi
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引用次数: 0

摘要

卵巢上皮肿瘤常见于成年人,患者发病年龄的中位数为 55 岁。在儿童中,上皮肿瘤很少见,且大多为良性。据报道,小于 15 岁的粘液性囊腺癌只有 11 例。本报告描述了一名 15 岁的阿曼女孩患卵巢粘液腺癌的病例。她因剧烈上腹痛和腹胀入院。CT 扫描显示,一个巨大的囊性病变从左侧附件产生,充满了整个腹腔和盆腔。患者接受了腹腔镜手术,进行了左侧卵巢囊肿切除术和网膜活检,结果显示左侧卵巢囊肿大小为 35 x 30 厘米,内充满稻草色浑浊液体。组织病理学报告为粘液腺癌。患者随后接受了囊肿切除手术,包括左侧输卵管切除术、网膜切除术、阑尾切除术和淋巴结清扫术,结果显示恶性肿瘤或转移性疾病均为阴性。随访期间,她的盆腔出现了淋巴结肿大,已进行了引流。随访期间没有其他重大问题,也没有复发或转移的迹象。卵巢上皮肿瘤在少女中很少见,恶性肿瘤更是凤毛麟角。对于这些患者,尽管根治性手术的复发率较高,但还是采用保留生育功能的手术。所有病例都应接受随访,以观察复发情况并及时处理。
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Mucinous Carcinoma of Ovary in a 15-Year-Old Girl, A Rare Case Report and Literature Review.

Ovarian epithelial tumors are common in adults, and the median patient age at presentation is 55 years. In children, epithelial tumors are rare and mostly benign. Mucinous cystadenocarcinoma is reported in only 11 cases less than 15 years old. This report describes the case of a 15-year-old postmenarchal Omani girl with ovarian mucinous carcinoma. She was admitted with severe epigastric pain and abdomen distension. CT scan showed a huge cystic lesion arising from the left adnexa filling the entire abdominal and pelvic cavity. The patient underwent laparotomy with left ovarian cystectomy and omental biopsy which revealed a 35 x 30 cm left ovarian cyst filled with turbid straw color fluid. Histopathology was reported as mucinous carcinoma. The patient later underwent cytoreductive surgery with left salpingo-oophorectomy, omentectomy, appendicectomy, and lymph node dissection that were negative for malignancy or metastatic disease. During follow-up, she developed a lymphocele in the pelvic cavity that was drained. There were no other significant issues during follow-up, as well as no evidence of recurrence or metastasis. Epithelial tumors of the ovary are rare in young girls, with malignant tumors being exceedingly rare. Fertility-sparing surgery is adopted over radical surgery in these patients, even though the recurrence rates with this treatment protocol are high. All cases should be under follow-up to look for recurrence and timely management.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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