[碳酸氢钠可逆转飞卡尼和拉科酰胺导致的心室内传导延迟临界]。

Innere Medizin (Heidelberg, Germany) Pub Date : 2024-12-01 Epub Date: 2024-08-21 DOI:10.1007/s00108-024-01768-2

Anja Gallinger, Rahman Osei-Davies, F Hennersdorf

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引用次数: 0

摘要

本文介绍了一例 72 岁女性患者的心律失常性晕厥病例，该患者在接受非卡尼和拉科萨胺联合治疗后出现心律失常性晕厥。作者认为这两种药物对心肌电压门控钠通道有相加作用，导致 QRS 异常增宽，临时起搏后出现出口阻滞，输注碳酸氢钠作为保底疗法后可完全逆转。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Reversibility of a critical intraventricular conduction delay under flecainide and lacosamide by sodium bicarbonate].

The case of a 72-year-old female patient with arrhythmogenic syncope associated with a combination therapy of flecainide and lacosamide is presented. The authors believe in an additive effect of both drugs on myocardial voltage-gated sodium channels with extraordinary QRS widening, exit block with temporary pacing and complete reversibility through infusion of sodium bicarbonate as bail-out therapy.

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Innere Medizin (Heidelberg, Germany)

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