Special Issue: Frontier Precise Measurement

Precision measurement has become an indispensable tool in modern scientific research, pushing the boundaries of our understanding across various analytical chemistry fields, including mass spectrometry, optical sensors, electrochemical detection, sample preparation, and software development. As technological advancements accelerate, the demand for highly accurate and reliable measurement techniques grows more critical. These precise measurements enable researchers to explore phenomena at unprecedented scales, from the subatomic level to macroscopic systems, providing insights that drive innovation and discovery. For this reason, we have invited leading experts to contribute their cutting-edge work, showcasing a broad spectrum of innovative methodologies and technologies that significantly advance the field of precision measurement. This special issue on “Frontier Precise Measurement” aims to highlight the latest developments and applications in this dynamic area of research.

In this special issue, we have invited chemists from a broad range of disciplines and expertise to showcase the diversity and activity of chemical and biological measurement. The issue features a diverse collection of articles covering various topics in precision measurement, including extraction, spectroscopy, sensors, electrochemical detection, mass spectrometry, and software development. The articles on novel extraction methods highlight advancements in the field, such as the work by Xia Liu on the synthesis, extraction, and purification of theaflavins. Jing Chen presents the development of magnetic solid phase adsorption techniques using novel composite materials. Xueqin Ding refines genomic DNA extraction methods for genetic analysis in wild boar populations. Hui-Ling Li explores using magnetic nanocomposites for the solid phase extraction of parabens. Spectroscopy is well-represented with studies like Yuelin Song's examination of the three-dimensional MS² spectrum for bile acid isomer differentiation.

The sensor-related articles cover a broad spectrum of innovative detection methods. Zhiqin Yuan explores morin as a ratiometric fluorescent probe for dopamine detection. Qing Zhou enhances electron transfer for ultrasensitive H₂O₂ detection. Zhanjun Yang develops an electrochemical immunosensor for detecting bovine interferon-gamma using gold nanoparticles. Rui Zou improves the electrochemiluminescence properties of graphite carbon nitride. Dong Xu develops a colorimetric sensor for lead ion detection using gold nanorods. Ruizhuo Ouyang explores the advancements in using perovskite materials for sensor applications. Wei-Bin Tseng focuses on the selective colorimetric detection of inorganic arsenic using homocysteine-modified gold nanoparticles. Jun-Ying Huang introduces a fluorescence probe based on iron oxide quantum dots for cytosine sensing. Te-Wei Chiu discusses the hydrothermal synthesis of terbium tungstate for determining 4-nitrophenol in water samples.

Mass spectrometry has rapidly evolved as a powerful tool for structural characterization and identification of unknown entities in a broad range of molecules. In the chemical space, Mei-Chun Tseng introduces a platform integrating NMR, crystallography, and ion mobility-mass spectrometry for characterization of iron azadiethylthiolate complexes. Few articles focus on protein modification and proteomic analysis. Shu-Hui Chen introduces a rapid one-pot microdroplet reaction combined with mass spectrometry for characterization of protein adduct in human blood. Yi-Ju Chen presents the development of a mass spectra library to enhance the profiling depth of tyrosine phosphoproteome using a hybrid DIA approach. Chien-Chen Lai conducts a comparative proteomics analysis of fibromyalgia and osteoarthritis using SWATH-based mass spectrometry. Software development articles include Cheng-Huang Lin's development of tools for real-time color analysis and tracking of solution reduction and Yi-Sheng Wang's introduction of MAXTOF, a software tool for optimizing the real-time MALDI-TOF MS measurements.

Chemistry plays a pivotal role in various facets of our daily lives, as well as in numerous scientific and industrial fields. For chemical societies, the publication of journals serves as a cornerstone for disseminating research findings, promoting scientific advancement, building a scientific community, and archiving knowledge. We express gratitude to the authors for their valuable contributions to this special issue. We hope that readers will thoroughly enjoy the content and find it inspiring for their future research endeavors.