泛素变甜了糖介导的泛素化调节 Nrf1 的功能

IF 16.6 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Molecular Cell Pub Date : 2024-08-22 DOI:10.1016/j.molcel.2024.07.023
Alison C. Mody, Christina M. Woo
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引用次数: 0

摘要

在本期的《分子细胞》(Molecular Cell)杂志上,Yoshida 等人1 报告了 Nrf1 上的一种非常规糖依赖泛素化事件,该事件破坏了 Nrf1 的转录激活。
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Ubiquitin gets sweet: Sugar-mediated ubiquitination regulates Nrf1 function

In this issue of Molecular Cell, Yoshida et al.1 report an unconventional sugar-dependent ubiquitination event on Nrf1 that disrupts Nrf1 transcriptional activation.

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来源期刊
Molecular Cell
Molecular Cell 生物-生化与分子生物学
CiteScore
26.00
自引率
3.80%
发文量
389
审稿时长
1 months
期刊介绍: Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.
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