对接受联合初级保健的 COVID-19 康复者进行为期一年的评估:全国范围内的前瞻性队列研究。

IF 3.9 3区 医学 Q1 REHABILITATION Annals of Physical and Rehabilitation Medicine Pub Date : 2024-08-21 DOI:10.1016/j.rehab.2024.101874
Marissa H.G. Gerards , Anne I. Slotegraaf , Arie C. Verburg , Hinke M. Kruizenga , Edith H.C. Cup , Johanna G. Kalf , Antoine F. Lenssen , Willemijn M. Meijer , Ângela Jornada Ben , Johanna M. van Dongen , Marian A.E. de van der Schueren , Maud J.L. Graff , Reinier P. Akkermans , Philip J. van der Wees , Thomas J. Hoogeboom , On behalf of the Dutch Consortium Allied Healthcare COVID-19
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引用次数: 0

摘要

背景:荷兰启动了一项全国性前瞻性队列研究:荷兰在全国范围内开展了一项前瞻性队列研究,以调查冠状病毒病 2019(COVID-19)康复者的康复轨迹以及初级保健专职医疗人员的治疗费用:该研究描述了 12 个月内冠状病毒病(COVID-19)康复者的康复轨迹和相关基线特征,这些康复者曾就诊于初级保健专职医疗人员。研究还旨在深入了解相关的医疗保健和社会成本:参与者在基线(即治疗开始时)、3、6、9 和 12 个月内填写了参与者报告的参与、健康相关生活质量、疲劳、身体功能和费用等标准化结果:共纳入 1451 名参与者(64% 为女性,76% 为轻度/中度患者),平均(标清)年龄为 49(12)岁。线性混合模型显示,从基线到 12 个月期间,所有结果指标均有明显的临床相关改善。在 6 个月至 12 个月期间,我们发现大多数结果指标都有显著改善,但与临床无关。基线得分越低是唯一一个与该结果随时间推移改善程度越大相关的基线因素。对于队列中的普通参与者而言,联合医疗总成本(平均为1921欧元;SEM为48欧元)约占社会总成本(平均为64584欧元;SEM为3149欧元)的3%:COVID-19康复者的健康状况在12个月的随访期间有了明显改善,但几乎所有改善都发生在基线和6个月之间。大多数参与者的日常生活仍然受到严重影响,并产生了巨大的社会成本。这些问题,再加上基线特征几乎无法解释随时间推移而出现的康复差异这一事实,凸显了持续关注COVID-19康复者管理的重要性。试验注册:clinicaltrials.gov (NCT04735744)。
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One-year evaluation of people recovering from COVID-19 receiving allied primary healthcare: A nationwide prospective cohort study

Background

A Dutch nationwide prospective cohort study was initiated to investigate recovery trajectories of people recovering from coronavirus disease 2019 (COVID-19) and costs of treatment by primary care allied health professionals.

Objectives

The study described recovery trajectories over a period of 12 months and associated baseline characteristics of participants recovering from COVID-19 who visited a primary care allied health professional. It also aimed to provide insight into the associated healthcare and societal costs.

Methods

Participants completed participant-reported standardized outcomes on participation, health-related quality of life, fatigue, physical functioning, and costs at baseline (ie, start of the treatment), 3, 6, 9 and 12 months.

Results

A total of 1451 participants (64 % women, 76 % mild/moderate severity) with a mean (SD) age of 49 (12) years were included. Linear mixed models showed significant and clinically relevant improvements over time in all outcome measures between baseline and 12 months. Between 6 and 12 months, we found significant but not clinically relevant improvements in most outcome measures. Having a worse baseline score was the only baseline factor that was consistently associated with greater improvement over time on that outcome. Total allied healthcare costs (mean €1921; SEM €48) made up about 3% of total societal costs (mean €64,584; SEM €3149) for the average participant in the cohort.

Conclusions

The health status of participants recovering from COVID-19 who visited an allied health professional improved significantly over a 12-month follow-up period, but nearly the improvement occurred between baseline and 6 months. Most participants still reported severe impairments in their daily lives, and generated substantial societal costs. These issues, combined with the fact that baseline characteristics explained little of the variance in recovery over time, underscore the importance of continued attention for the management of people recovering from COVID-19.

Trial registration

clinicaltrials.gov (NCT04735744)

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来源期刊
CiteScore
7.80
自引率
4.30%
发文量
136
审稿时长
34 days
期刊介绍: Annals of Physical and Rehabilitation Medicine covers all areas of Rehabilitation and Physical Medicine; such as: methods of evaluation of motor, sensory, cognitive and visceral impairments; acute and chronic musculoskeletal disorders and pain; disabilities in adult and children ; processes of rehabilitation in orthopaedic, rhumatological, neurological, cardiovascular, pulmonary and urological diseases.
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