通过临床元基因组学鉴定巴西的一种 Orthohantavirus 菌株。

IF 2.1 4区医学 Q3 INFECTIOUS DISEASES Diagnostic microbiology and infectious disease Pub Date : 2024-08-22 DOI:10.1016/j.diagmicrobio.2024.116501

Gabriel J. Seara-Morais , Fernando Franco de Oliveira Miraglia , Jairo Tabacow Hidal , Luis Fernando Aranha Camargo , Cristóvão Luis Pitangueira Mangueira , Andre Mario Doi , Deyvid Emanuel Amgarten , Erick Gustavo Dorlass , Rubia Anita Ferraz Santana , João Renato Rebello Pinho

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引用次数: 0

摘要

我们描述了一例 33 岁男性病例，患者发热、肌痛、恶心和气喘已持续 6 天。患者居住在农村地区。最初的假设包括虫媒病毒感染、病毒性肝炎和莱姆病。登革热、寨卡和基孔肯雅病毒的逆转录酶聚合酶链反应（RT-PCR）检测结果均为阴性。我们能够在正泛病毒基因组中恢复完整的 S、L 和 M 病毒片段。

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Identification of a Orthohantavirus strain by clinical metagenomics in Brazil

We describe a case of a 33-year-old male presented with fever, myalgia, nausea, and asthenia for six days. The patient lived in a rural area. Initial hypotheses included arbovirus infection, viral hepatitis, and Lyme disease. Reverse transcriptase polymerase chain reaction (RT-PCR) tests for Dengue, Zika, and Chikungunya resulted negative. We were able to recover complete S, L, and M segments of virus in the Orthohantavirus genome.

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.