耐甲氧西林金黄色葡萄球菌 (MRSA) 纳氏试验在全身性抗葡萄球菌抗菌治疗初期的持续阳性反应。

IF 3.8 3区医学 Q2 INFECTIOUS DISEASES American journal of infection control Pub Date : 2025-01-01 Epub Date: 2024-08-23 DOI:10.1016/j.ajic.2024.08.014

Maximillian S Wu, Wesley Kufel, Scott Riddell, Jeff Steele, Elizabeth Asiago-Reddy

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引用次数: 0

摘要

接受全身性抗 MRSA 抗菌药物治疗的患者鼻腔内耐甲氧西林金黄色葡萄球菌（MRSA）核酸检测呈阳性的典型持续时间尚不清楚。在这项研究中，对初次 MRSA 鼻腔核酸检测呈阳性的住院成人患者，在处方全身性抗 MRSA 抗菌药物 48-96 小时后进行了随访检测。100/113（88.5%）例患者的后续检测结果呈阳性，这表明 MRSA 鼻腔 DNA 检测在患者开始接受抗 MRSA 治疗后仍有筛查作用。

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Persistent methicillin-resistant Staphylococcus aureus (MRSA) nares test positivity during initial days of systemic antistaphylococcal antimicrobial therapy.

The typical duration of positive nucleic acid tests for methicillin-resistant Staphylococcus aureus (MRSA) in the nares of patients receiving systemic anti-MRSA antimicrobials is unknown. In this study, hospitalized adult patients with an initial positive MRSA nares nucleic acid test prescribed systemic anti-MRSA antimicrobials had follow-up testing done 48 to 96 hours later. A positive follow-up test was detected in 100/113 (88.5%), indicating that MRSA nares DNA tests still have utility for screening after patients have initiated anti-MRSA therapy.

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来源期刊

American journal of infection control 医学-传染病学

CiteScore

7.40

自引率

4.10%

发文量

479

审稿时长

24 days

期刊介绍： AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)