癌症治疗相关的心功能障碍：增强心脏康复的策略。

Q2 Medicine Methodist DeBakey cardiovascular journal Pub Date : 2024-08-20 eCollection Date: 2024-01-01 DOI:10.14797/mdcvj.1430

Pavel Martinez-Dominguez, Maria Jose Santa Ana-Bayona, Enrique C Guerra, Nilda Espinola-Zavaleta

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引用次数: 0

摘要

化疗明显改善了癌症的治疗效果，但与癌症治疗相关的心功能不全（CTRCD）仍是一项重大挑战，约有 10% 的患者会受到影响。CTRCD 可无症状或伴有心衰症状。多模态成像，尤其是超声心动图，仍然是监测心功能的关键。评估 CTRCD 的潜在生物标志物包括肌钙蛋白和 B 型钠尿肽。药物干预，如右雷佐生、血管紧张素转换酶抑制剂和他汀类药物，在初级预防和减轻心脏毒性以及心脏康复计划中发挥着至关重要的作用。因此，综合方法对于实现最佳心脏康复和改善患者预后至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cancer Therapy-Related Cardiac Dysfunction: Strategies for Enhancing Cardiac Recovery.

Chemotherapy has markedly improved cancer outcomes, yet cancer therapy-related cardiac dysfunction (CTRCD) poses a significant challenge, affecting around 10% of patients. CTRCD can be asymptomatic or present with heart failure symptoms. Multimodality imaging, particularly echocardiography, remains pivotal for monitoring cardiac function. Potential biomarkers for CTRCD assessment include troponin and B-type natriuretic peptide. Pharmacological interventions, such as dexrazoxane, angiotensin-converting enzyme inhibitors, and statins, play a crucial role in primary prevention and mitigating cardiotoxicity alongside cardiac rehabilitation programs. Thus, a comprehensive approach is essential for optimal cardiac recovery and improved patient outcomes.

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来源期刊

Methodist DeBakey cardiovascular journal Medicine-Medicine (all)

CiteScore

2.30

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0.00%

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