急性冠状动脉综合征右冠状动脉动脉瘤的经皮冠状动脉介入治疗:RIGHTMARE 登记结果。

IF 1.6 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Cardiovascular Revascularization Medicine Pub Date : 2024-08-22 DOI:10.1016/j.carrev.2024.08.013
Giulio Piedimonte, Enrico Cerrato, Cristina Rolfo, Ivan J Nunez Gil, Lorenzo Azzalini, Riccardo Mangione, Francesco Maiellaro, Alberto Boi, Donovan Riganelli, Andrea Sardone, Francesco Bruno, Fernando Scudiero, Giampiero Vizzari, Gabriele Carciotto, Dario Calderone, Marco Borgi, Francesco Paolo Cancro, Ivan Sanchez, Massimo Leoncini, Emanuele Sagazio, Francesco Colombo, Gabriele Rosso, Tania Chechi, Simone Zecchino, Marco Pavani, Alfonso Franzè, Greca Zanda, Manuel Bosco, Jose Maria De La Torre Hernandez, Antonio Micari, Gennaro Galasso, Francesco Versaci, Corrado Tamburino, Giuseppe Patti, Alessio La Manna, Francesco Tomassini, Ferdinando Varbella
{"title":"急性冠状动脉综合征右冠状动脉动脉瘤的经皮冠状动脉介入治疗:RIGHTMARE 登记结果。","authors":"Giulio Piedimonte, Enrico Cerrato, Cristina Rolfo, Ivan J Nunez Gil, Lorenzo Azzalini, Riccardo Mangione, Francesco Maiellaro, Alberto Boi, Donovan Riganelli, Andrea Sardone, Francesco Bruno, Fernando Scudiero, Giampiero Vizzari, Gabriele Carciotto, Dario Calderone, Marco Borgi, Francesco Paolo Cancro, Ivan Sanchez, Massimo Leoncini, Emanuele Sagazio, Francesco Colombo, Gabriele Rosso, Tania Chechi, Simone Zecchino, Marco Pavani, Alfonso Franzè, Greca Zanda, Manuel Bosco, Jose Maria De La Torre Hernandez, Antonio Micari, Gennaro Galasso, Francesco Versaci, Corrado Tamburino, Giuseppe Patti, Alessio La Manna, Francesco Tomassini, Ferdinando Varbella","doi":"10.1016/j.carrev.2024.08.013","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The optimal strategy during percutaneous coronary intervention (PCI) of aneurysmatic right coronary artery (ARCA) remains uncertain and has never been tested in the acute setting.</p><p><strong>Objectives: </strong>To compare the in-hospital and long-term outcomes of immediate and staged PCI strategies for ARCA as culprit lesions during acute coronary syndrome (ACS).</p><p><strong>Methods: </strong>Among 102.376 PCIs performed in 18 European centers, a total of 85 patients presenting with acute coronary syndrome undergoing ARCA PCI were finally included in the analysis. PCI strategy (stenting performed during the immediate vs staged procedure) and pharmacological approach adopted were collected. The primary outcome was procedural success (technical success without in-hospital MACE).</p><p><strong>Results: </strong>The primary outcome occurred in 48.2 % of cases, with no significant differences observed between the immediate and staged PCI groups (50.9 % vs 43.3 %, p = 0.504). Patients in the staged-PCI group had a significantly higher rate of intravenous anticoagulant use (83.3 % vs 48.1 %, p = 0.002), BARC type 3 and 5 bleedings (12.9 % vs 1.9 %, p = 0.037), and longer in-hospital stay (7.40 ± 5.11 vs 9.5 ± 5.25 days, p = 0.049). After multivariate analysis, no independent predictors for procedural success were found in either group. Target lesion failure occurred in 24.1 % of cases without differences between groups at a median follow-up of three years.</p><p><strong>Conclusions: </strong>Among patients undergoing ARCA PCI in the setting of ACS, immediate or staged PCI were associated with similar in-hospital and long-term outcomes. However, staged PCI was associated with a higher risk of major bleeding events and longer length of stay compared to immediate PCI strategy.</p>","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Percutaneous coronary interventions for aneurysmatic right coronary artery in acute coronary syndrome: RIGHTMARE registry outcomes.\",\"authors\":\"Giulio Piedimonte, Enrico Cerrato, Cristina Rolfo, Ivan J Nunez Gil, Lorenzo Azzalini, Riccardo Mangione, Francesco Maiellaro, Alberto Boi, Donovan Riganelli, Andrea Sardone, Francesco Bruno, Fernando Scudiero, Giampiero Vizzari, Gabriele Carciotto, Dario Calderone, Marco Borgi, Francesco Paolo Cancro, Ivan Sanchez, Massimo Leoncini, Emanuele Sagazio, Francesco Colombo, Gabriele Rosso, Tania Chechi, Simone Zecchino, Marco Pavani, Alfonso Franzè, Greca Zanda, Manuel Bosco, Jose Maria De La Torre Hernandez, Antonio Micari, Gennaro Galasso, Francesco Versaci, Corrado Tamburino, Giuseppe Patti, Alessio La Manna, Francesco Tomassini, Ferdinando Varbella\",\"doi\":\"10.1016/j.carrev.2024.08.013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The optimal strategy during percutaneous coronary intervention (PCI) of aneurysmatic right coronary artery (ARCA) remains uncertain and has never been tested in the acute setting.</p><p><strong>Objectives: </strong>To compare the in-hospital and long-term outcomes of immediate and staged PCI strategies for ARCA as culprit lesions during acute coronary syndrome (ACS).</p><p><strong>Methods: </strong>Among 102.376 PCIs performed in 18 European centers, a total of 85 patients presenting with acute coronary syndrome undergoing ARCA PCI were finally included in the analysis. PCI strategy (stenting performed during the immediate vs staged procedure) and pharmacological approach adopted were collected. The primary outcome was procedural success (technical success without in-hospital MACE).</p><p><strong>Results: </strong>The primary outcome occurred in 48.2 % of cases, with no significant differences observed between the immediate and staged PCI groups (50.9 % vs 43.3 %, p = 0.504). Patients in the staged-PCI group had a significantly higher rate of intravenous anticoagulant use (83.3 % vs 48.1 %, p = 0.002), BARC type 3 and 5 bleedings (12.9 % vs 1.9 %, p = 0.037), and longer in-hospital stay (7.40 ± 5.11 vs 9.5 ± 5.25 days, p = 0.049). After multivariate analysis, no independent predictors for procedural success were found in either group. Target lesion failure occurred in 24.1 % of cases without differences between groups at a median follow-up of three years.</p><p><strong>Conclusions: </strong>Among patients undergoing ARCA PCI in the setting of ACS, immediate or staged PCI were associated with similar in-hospital and long-term outcomes. However, staged PCI was associated with a higher risk of major bleeding events and longer length of stay compared to immediate PCI strategy.</p>\",\"PeriodicalId\":47657,\"journal\":{\"name\":\"Cardiovascular Revascularization Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2024-08-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cardiovascular Revascularization Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.carrev.2024.08.013\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiovascular Revascularization Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.carrev.2024.08.013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0

摘要

背景:动脉瘤右冠状动脉(ARCA)经皮冠状动脉介入治疗(PCI动脉瘤性右冠状动脉(ARCA)经皮冠状动脉介入治疗(PCI)的最佳策略仍不确定,且从未在急性病例中进行过测试:目的:比较急性冠状动脉综合征(ACS)期间作为罪魁祸首的ARCA立即和分阶段PCI策略的院内和长期疗效:在欧洲18个中心进行的102376例PCI手术中,共有85例急性冠状动脉综合征患者接受了ARCA PCI治疗,最终纳入分析。分析收集了患者的 PCI 策略(即刻手术与分阶段手术中的支架植入)和采用的药物治疗方法。主要结果是手术成功率(技术成功且无院内MACE):结果:48.2%的病例获得了主要结果,立即PCI组和分期PCI组之间没有观察到显著差异(50.9% vs 43.3%,P = 0.504)。分期 PCI 组患者的静脉抗凝剂使用率(83.3% vs 48.1%,p = 0.002)、BARC 3 型和 5 型出血率(12.9% vs 1.9%,p = 0.037)和住院时间(7.40 ± 5.11 vs 9.5 ± 5.25 天,p = 0.049)均明显更高。经过多变量分析,两组患者均未发现手术成功的独立预测因素。靶病变失败发生率为24.1%,中位随访三年,两组间无差异:结论:在接受ARCA PCI治疗的ACS患者中,立即或分期PCI与相似的院内和长期预后相关。然而,与立即PCI策略相比,分期PCI与更高的大出血风险和更长的住院时间相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Percutaneous coronary interventions for aneurysmatic right coronary artery in acute coronary syndrome: RIGHTMARE registry outcomes.

Background: The optimal strategy during percutaneous coronary intervention (PCI) of aneurysmatic right coronary artery (ARCA) remains uncertain and has never been tested in the acute setting.

Objectives: To compare the in-hospital and long-term outcomes of immediate and staged PCI strategies for ARCA as culprit lesions during acute coronary syndrome (ACS).

Methods: Among 102.376 PCIs performed in 18 European centers, a total of 85 patients presenting with acute coronary syndrome undergoing ARCA PCI were finally included in the analysis. PCI strategy (stenting performed during the immediate vs staged procedure) and pharmacological approach adopted were collected. The primary outcome was procedural success (technical success without in-hospital MACE).

Results: The primary outcome occurred in 48.2 % of cases, with no significant differences observed between the immediate and staged PCI groups (50.9 % vs 43.3 %, p = 0.504). Patients in the staged-PCI group had a significantly higher rate of intravenous anticoagulant use (83.3 % vs 48.1 %, p = 0.002), BARC type 3 and 5 bleedings (12.9 % vs 1.9 %, p = 0.037), and longer in-hospital stay (7.40 ± 5.11 vs 9.5 ± 5.25 days, p = 0.049). After multivariate analysis, no independent predictors for procedural success were found in either group. Target lesion failure occurred in 24.1 % of cases without differences between groups at a median follow-up of three years.

Conclusions: Among patients undergoing ARCA PCI in the setting of ACS, immediate or staged PCI were associated with similar in-hospital and long-term outcomes. However, staged PCI was associated with a higher risk of major bleeding events and longer length of stay compared to immediate PCI strategy.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Cardiovascular Revascularization Medicine
Cardiovascular Revascularization Medicine CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.30
自引率
5.90%
发文量
687
审稿时长
36 days
期刊介绍: Cardiovascular Revascularization Medicine (CRM) is an international and multidisciplinary journal that publishes original laboratory and clinical investigations related to revascularization therapies in cardiovascular medicine. Cardiovascular Revascularization Medicine publishes articles related to preclinical work and molecular interventions, including angiogenesis, cell therapy, pharmacological interventions, restenosis management, and prevention, including experiments conducted in human subjects, in laboratory animals, and in vitro. Specific areas of interest include percutaneous angioplasty in coronary and peripheral arteries, intervention in structural heart disease, cardiovascular surgery, etc.
期刊最新文献
Left atrial appendage occlusion in patients with amyloidosis: a nationwide cohort analysis. Real-world outcomes and management considerations following surgical aortic valve replacement with the Trifecta valve. Trends in utilization and clinical outcomes with and without the use of distal filter wire embolic protection devices. Validation of the coronary artery specific chronic total occlusion percutaneous coronary intervention angiographic difficulty scores in the PROGRESS-CTO registry. Surviving venoarterial extracorporeal membrane oxygenation (VA-ECMO): The roles of severity scores and post-operative lactate clearance.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1