[磁疲劳试验揭示的多灶性运动神经病与运动性慢性炎症性脱髓鞘多发性神经病的边缘病例]。

Q4 Medicine Clinical Neurology Pub Date : 2024-09-26 Epub Date: 2024-08-24 DOI:10.5692/clinicalneurol.cn-001974
Ryo Fukunaga, Nobuhiro Ogawa, Toshika Hata, Hiroyuki Yabata, Isamu Yamakawa, Makoto Urushitani
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引用次数: 0

摘要

一名 26 岁的女性患者左上肢无力已有 7 个月的病史,几周后发展到抬起手臂都很困难。她的症状时好时坏。在过去的三个月中,她因下肢近端无力而无法站立。神经传导检查未显示任何明确的传导阻滞或异常的感觉传导,但运动传导检查显示末端潜伏期略有延长,F 波频率下降。磁疲劳测试显示存在近端传导阻滞。经静脉注射免疫球蛋白治疗后,她的症状迅速缓解,最终被诊断为慢性免疫介导的神经病,同时符合多灶性运动神经病(MMN)和运动性慢性炎症性脱髓鞘多发性神经病(CIDP)的标准。我们的病例凸显了磁疲劳试验在检测传导阻滞方面的实用性及其在区分多灶性运动神经病和运动型慢性炎症性脱髓鞘多发性神经病方面的作用。
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[A borderline case between multifocal motor neuropathy and motor chronic inflammatory demyelinating polyneuropathy revealed by the magnetic fatigue test].

A 26-year-old woman presented with a seven-month history of weakness in her left upper limb, progressing to difficulty lifting her arms within a few weeks. Her symptoms progressed with fluctuations. For the past three months, she has been unable to stand due to weakness in her proximal lower limbs. Nerve conduction studies did not show any definite conduction block or abnormal sensory conduction, but motor conduction studies showed a slight prolongation of the terminal latency and a decrease in the frequency of the F-wave. A magnetic fatigue test indicated a proximal conduction block. Her symptoms were rapidly resolved with intravenous immunoglobulin treatment, leading to a diagnosis of chronic immune-mediated neuropathy, met both criteria for multifocal motor neuropathy (MMN) and motor chronic inflammatory demyelinating polyneuropathy (CIDP). Our case highlights the utility of the magnetic fatigue test in detecting conduction blocks and its role in differentiating between MMN and motor CIDP.

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来源期刊
Clinical Neurology
Clinical Neurology Medicine-Neurology (clinical)
CiteScore
0.30
自引率
0.00%
发文量
147
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