{"title":"海藻多糖:来源、结构和生物医学应用,特别强调抗病毒潜力","authors":"","doi":"10.1016/j.fufo.2024.100440","DOIUrl":null,"url":null,"abstract":"<div><p>Seaweeds are incredibly significant marine resources that have the ability to yield beneficial metabolites and bioactive substances, exhibiting an extensive variety of biological and physiological capabilities. Seaweed polysaccharides, in conjunction with other bioactive components, have been shown to exhibit a diverse range of advantageous characteristics. These include antioxidant, anticoagulant, anti-inflammatory, antiviral, and anticarcinogenic effects. The assortment and constitution of polysaccharides found in seaweed are crucial factors in regulating these biological processes. Agar, alginate, carrageenan, fucoidan, and ulvan are abundant in seaweeds, boosting their bioactivity. Tissue engineering, drug administration, and wound healing are among the medical applications of seaweed polysaccharides. Algae-derived polysaccharides have exhibited extraordinary antiviral properties, which makes them highly promising subjects for pharmacological research. Moreover, numerous mechanisms have been recorded for these polysaccharides, encompassing the prevention of viral coupling or entry of the cell host, along with the inhibition of DNA replication and protein synthesis. Seaweed polysaccharides also have the potential to serve as a long-term solution against the highly publicized coronavirus, which has caused a global pandemic. This review aims to analyze a variety of seaweed-derived polysaccharides, explore the association between their bioactivity and structural compositions, and highlight their potential biological applications, particularly in relation to antiviral activity.</p></div>","PeriodicalId":34474,"journal":{"name":"Future Foods","volume":null,"pages":null},"PeriodicalIF":7.2000,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666833524001461/pdfft?md5=146d8d8dd78895d9863776a6b3768cd2&pid=1-s2.0-S2666833524001461-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Seaweed polysaccharides: Sources, structure and biomedical applications with special emphasis on antiviral potentials\",\"authors\":\"\",\"doi\":\"10.1016/j.fufo.2024.100440\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Seaweeds are incredibly significant marine resources that have the ability to yield beneficial metabolites and bioactive substances, exhibiting an extensive variety of biological and physiological capabilities. Seaweed polysaccharides, in conjunction with other bioactive components, have been shown to exhibit a diverse range of advantageous characteristics. These include antioxidant, anticoagulant, anti-inflammatory, antiviral, and anticarcinogenic effects. The assortment and constitution of polysaccharides found in seaweed are crucial factors in regulating these biological processes. Agar, alginate, carrageenan, fucoidan, and ulvan are abundant in seaweeds, boosting their bioactivity. Tissue engineering, drug administration, and wound healing are among the medical applications of seaweed polysaccharides. Algae-derived polysaccharides have exhibited extraordinary antiviral properties, which makes them highly promising subjects for pharmacological research. Moreover, numerous mechanisms have been recorded for these polysaccharides, encompassing the prevention of viral coupling or entry of the cell host, along with the inhibition of DNA replication and protein synthesis. Seaweed polysaccharides also have the potential to serve as a long-term solution against the highly publicized coronavirus, which has caused a global pandemic. This review aims to analyze a variety of seaweed-derived polysaccharides, explore the association between their bioactivity and structural compositions, and highlight their potential biological applications, particularly in relation to antiviral activity.</p></div>\",\"PeriodicalId\":34474,\"journal\":{\"name\":\"Future Foods\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":7.2000,\"publicationDate\":\"2024-08-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2666833524001461/pdfft?md5=146d8d8dd78895d9863776a6b3768cd2&pid=1-s2.0-S2666833524001461-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Future Foods\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666833524001461\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Foods","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666833524001461","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
海藻是极其重要的海洋资源,能够产生有益的代谢物和生物活性物质,具有广泛的生物和生理功能。海藻多糖与其他生物活性成分结合在一起,显示出多种多样的优势特性。其中包括抗氧化、抗凝血、抗炎、抗病毒和抗癌作用。海藻中多糖的种类和组成是调节这些生物过程的关键因素。海藻中含有丰富的琼脂、海藻酸、卡拉胶、褐藻糖胶和藻蓝蛋白,这些物质增强了海藻的生物活性。组织工程、给药和伤口愈合是海藻多糖的医学应用领域。海藻多糖具有非凡的抗病毒特性,这使其成为极具潜力的药理学研究对象。此外,这些多糖还具有多种机制,包括防止病毒耦合或进入细胞宿主,以及抑制 DNA 复制和蛋白质合成。海藻多糖还有可能作为一种长期的解决方案,来对付引起全球大流行的、广为人知的冠状病毒。本综述旨在分析各种海藻多糖,探讨其生物活性与结构组成之间的联系,并重点介绍其潜在的生物应用,尤其是与抗病毒活性有关的应用。
Seaweed polysaccharides: Sources, structure and biomedical applications with special emphasis on antiviral potentials
Seaweeds are incredibly significant marine resources that have the ability to yield beneficial metabolites and bioactive substances, exhibiting an extensive variety of biological and physiological capabilities. Seaweed polysaccharides, in conjunction with other bioactive components, have been shown to exhibit a diverse range of advantageous characteristics. These include antioxidant, anticoagulant, anti-inflammatory, antiviral, and anticarcinogenic effects. The assortment and constitution of polysaccharides found in seaweed are crucial factors in regulating these biological processes. Agar, alginate, carrageenan, fucoidan, and ulvan are abundant in seaweeds, boosting their bioactivity. Tissue engineering, drug administration, and wound healing are among the medical applications of seaweed polysaccharides. Algae-derived polysaccharides have exhibited extraordinary antiviral properties, which makes them highly promising subjects for pharmacological research. Moreover, numerous mechanisms have been recorded for these polysaccharides, encompassing the prevention of viral coupling or entry of the cell host, along with the inhibition of DNA replication and protein synthesis. Seaweed polysaccharides also have the potential to serve as a long-term solution against the highly publicized coronavirus, which has caused a global pandemic. This review aims to analyze a variety of seaweed-derived polysaccharides, explore the association between their bioactivity and structural compositions, and highlight their potential biological applications, particularly in relation to antiviral activity.