[哮喘中嗜酸性粒细胞异质性的研究进展]。

Q3 Medicine 生理学报 Pub Date : 2024-08-25

Yan Chen, Song-Min Ying, Chao Zhang

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引用次数: 0

摘要

哮喘是一种以慢性气道炎症为特征的异质性疾病。一半以上的哮喘病例是由过敏原诱发的。嗜酸性粒细胞在气道中大量聚集，其数量与哮喘的严重程度密切相关。近年来，人们对嗜酸性粒细胞在哮喘中的发病机制以及针对嗜酸性粒细胞的靶向治疗药物进行了广泛的研究。本文主要综述了嗜酸性粒细胞异质性在哮喘发生、发展中重要作用的研究进展，为今后哮喘的个性化精准治疗提供思路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Research progress on eosinophil heterogeneity in asthma].

Asthma is a heterogeneous disease characterized by chronic airway inflammation. More than half of asthma cases are induced by allergens. Eosinophils accumulate in large numbers in the airways, and their number is closely related to the severity of asthma. In recent years, extensive research has been conducted on the pathogenesis of eosinophils in asthma and the targeted therapeutic drugs for them. This article mainly reviews the research progress on the important role of eosinophil heterogeneity in the occurrence and development of asthma, and provides ideas for the personalized and precise treatment of asthma in the future.

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来源期刊

生理学报 Medicine-Medicine (all)

CiteScore

1.20

自引率

0.00%

发文量

4820

期刊介绍： Acta Physiologica Sinica (APS) is sponsored by the Chinese Association for Physiological Sciences and Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences (CAS), and is published bimonthly by the Science Press, China. APS publishes original research articles in the field of physiology as well as research contributions from other biomedical disciplines and proceedings of conferences and symposia of physiological sciences. Besides “Original Research Articles”, the journal also provides columns as “Brief Review”, “Rapid Communication”, “Experimental Technique”, and “Letter to the Editor”. Articles are published in either Chinese or English according to authors’ submission.