过渡时期的导航:儿童炎症性肠病的多学科方法。

IF 1.5 3区 医学 Q2 PEDIATRICS Pediatric Surgery International Pub Date : 2024-08-27 DOI:10.1007/s00383-024-05789-8
A Raffaele, C M Ferlini, G Fusi, M V Lenti, E Cereda, S M E Caimmi, M Bertozzi, G Riccipetitoni
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引用次数: 0

摘要

目的:多学科方法治疗炎症性肠病(IBD)最近在儿科患者中产生了积极影响,降低了辍学率并促进了向成人护理的过渡。我们的研究旨在评估这种方法如何影响疾病活动、辍学率和过渡:我们进行了一项纵向观察研究,研究对象包括所有在儿童至青少年时期被诊断为 IBD 的患者,随访期至少为 12 个月。每位患者的终点包括治疗方法、手术需求和转归特征:我们共纳入了 19 名患者:结果:我们纳入了 19 名患者:13 名溃疡性结肠炎(UC)患者和 6 名克罗恩病(CD)患者。大多数患者需要接受多线治疗,两组患者中均有50%以上接受生物药物治疗。患者的依从性良好,两组均有一名患者退出治疗(10 人,5%)。与 UC 组相比,CD 组需要手术治疗的比例明显更高(16% 对 7.7%,P 结论:我们的经验表明,多学科综合疗法能帮助患者在最短的时间内治愈疾病:根据我们的经验,多学科方法治疗过渡年龄段患者的 IBD 似乎能有效实现临床缓解,并有可能减少治疗中途退出的情况。
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Navigating the transition: a multidisciplinary approach to inflammatory bowel disease in children.

Purpose: A multidisciplinary approach to Inflammatory Bowel Disease (IBD) has recently demonstrated a positive impact in pediatric patients, reducing dropout rates and facilitating the transition to adult care. Our study aims to evaluate how this approach influences disease activity, dropout rates, and transition.

Methods: We conducted a longitudinal observational study including all patients diagnosed with IBD during pediatric-adolescent age, with a minimum follow-up period of 12 months. For each patient, endpoints included therapeutic approach, need for surgery and transition features.

Results: We included 19 patients: 13 with Ulcerative Colitis (UC) and 6 with Crohn's disease (CD). Most patients required multiple lines of therapy, with over 50% in both groups receiving biological drugs. Compliance was good, with a single dropout in each group (10, 5%). The need for surgery was significantly higher in the CD group compared to the UC group (16% vs. 7.7%, p < 0.01). Mean age at transition was significantly higher in the UC group compared to the CD group (19.2 ± 0.7 years SD vs. 18.3 ± 0.6 years SD, p < 0.05).

Conclusions: In our experience, the multidisciplinary approach to IBD in transition-age patients appears effective in achieving clinical remission, offering the potential to reduce therapeutic dropouts.

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来源期刊
CiteScore
3.00
自引率
5.60%
发文量
215
审稿时长
3-6 weeks
期刊介绍: Pediatric Surgery International is a journal devoted to the publication of new and important information from the entire spectrum of pediatric surgery. The major purpose of the journal is to promote postgraduate training and further education in the surgery of infants and children. The contents will include articles in clinical and experimental surgery, as well as related fields. One section of each issue is devoted to a special topic, with invited contributions from recognized authorities. Other sections will include: -Review articles- Original articles- Technical innovations- Letters to the editor
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