一名健康男性因褪黑素诱发症状性心动过缓:病例报告。

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Oxford Medical Case Reports Pub Date : 2024-08-26 eCollection Date: 2024-08-01 DOI:10.1093/omcr/omae096
Asim Alawad, Wala Sati, Sara M I Ahmed, Moayed Elgassim, Mohamad Elgassim, Abderahman Balal
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引用次数: 0

摘要

褪黑素是一种与昼夜节律密切相关的松果体激素,在过去的几年里,褪黑素已成为一种非处方药物,用于治疗睡眠障碍。虽然人们普遍认为褪黑素是安全的,但最近的研究表明,它对人体的心率和血压有负面的肌力和时动力作用。一些研究表明,褪黑素会诱导心脏迷走神经张力,影响心率和平均动脉压。目前,关于褪黑激素除睡眠功能外的作用的文献有限。我们介绍了一个病例:一名 22 岁的健康男性在摄入 20 毫克褪黑素后到急诊科就诊,报告心悸和头晕。随后的检查发现他有明显的心动过缓。幸运的是,经过几个小时的观察,患者的心动过缓症状自发缓解,无需进行干预。
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Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case report.

Melatonin, a pineal gland hormone closely associated with the circadian rhythm, has been trending over the past years as an over-the-counter medication to aid with sleep disturbances. Although generally believed to be safe, recent studies show negative inotropic and chronotropic effects on the heart rate and blood pressure in humans. Several studies suggested that melatonin induces cardiac vagal tone and affects heart rate and mean arterial pressure. Limited literature is currently available on the effects of melatonin beyond its sleep function. We present a case of a healthy 22-year-old male who visited the emergency department reporting palpitations and dizziness following the ingestion of 20 mg of melatonin. Subsequent examinations revealed marked bradycardia. Fortunately, the patient experienced spontaneous resolution of the bradycardia without necessitating intervention after a few hours of observation, and he was observed and discharged.

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来源期刊
Oxford Medical Case Reports
Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
125
审稿时长
19 weeks
期刊介绍: Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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