苯二氮卓类药物和催眠药

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摘要

失眠会导致日间功能受损,降低生活质量。有效的治疗对于减轻患者的痛苦非常重要。针对失眠的认知行为疗法在面对面治疗和数字化治疗中都很有效,应作为短期或长期失眠的一线选择。如果非药物治疗无效或不适合,可以使用催眠药或镇静剂,但由于相关的不良反应,应仅限于短期使用。应逐渐停止治疗,以降低焦虑反弹、其他痛苦症状、意识混乱和抽搐的风险。褪黑素是一种可供选择的催眠药,可用于短期治疗 55 岁人群的失眠症。在认知行为疗法无效的慢性失眠症患者中,可选择奥列克素受体拮抗剂。
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Benzodiazepines and hypnotics

Insomnia can result in impaired daytime functioning and reduced quality of life. Effective treatment is important to reduce suffering. Cognitive behavioural therapy for insomnia is efficacious both in-person and digitally and should be the first-line option in either short-term or long-term insomnia. Hypnotics or sedatives can be offered if non-drug treatments are ineffective or unsuitable but should be kept to short-term use because of associated adverse effects. Treatment should be withdrawn gradually to reduce risks of rebound anxiety, other distressing symptoms, confusion and convulsions. Melatonin is an alternative hypnotic for the short-term management of insomnia in individuals aged >55 years. Orexin receptor antagonists are an option in chronic insomnia where cognitive behaviour approaches are not an option.

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Contents Editorial Board Editorial: Medical problems in pregnancy Management of pre-gestational diabetes in pregnancy Endocrine disorders in pregnancy
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