博雷纳牧区艾滋病毒/艾滋病患者存活时间的决定因素:埃塞俄比亚东南部亚贝洛综合医院的一项研究。

IF 2.1 4区 医学 Q3 INFECTIOUS DISEASES AIDS Research and Therapy Pub Date : 2024-08-28 DOI:10.1186/s12981-024-00644-1
Galgalo Jaba Nura, Kumbi Sara Wario, Markos Abiso Erango
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引用次数: 0

摘要

导言:艾滋病毒/艾滋病是全球最危险的疾病之一,影响着公共卫生、经济、社会、政治问题和社区。据世界卫生组织估计,截至 2023 年,将有 4040 万人感染艾滋病毒/艾滋病。本研究旨在确定亚贝洛综合医院博雷纳牧区艾滋病毒/艾滋病患者存活时间的决定因素:研究设计为回顾性队列研究,根据记录的数据,样本量为 293 名艾滋病毒/艾滋病感染者。本研究采用卡普兰-梅耶图、对数秩检验和考克斯比例危险模型分析等生存模型进行分析:在所有样本中,179 人(61.1%)为女性,114 人(38.1%)为男性。在这些男性中,有 36 人(31.6%)已经死亡。使用 Cox 比例危险模型进行的分析表明,以下变量与艾滋病病毒/艾滋病患者的存活时间显著相关:性别、教育状况、居住地区、结核病(TB)和机会性感染:我们得出的结论是,与农村地区的艾滋病毒/艾滋病感染者相比,城市地区的艾滋病毒/艾滋病感染者的死亡风险较低,这表明农村居民的生存概率较低。因此,博雷纳区政府应重点关注成年患者,以提高他们的预期寿命。
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Determinants of survival time for HIV/AIDS patients in the pastoralist region of Borena: a study at Yabelo General Hospital, South East Ethiopia.

Introduction: HIV/AIDS is one of the most dangerous diseases globally, impacting public health, economics, society, political issues, and communities. As of 2023, the World Health Organization estimates that 40.4 million people are living with HIV/AIDS. This study aimed to identify the determinants of survival time for HIV/AIDS patients in the pastoralist region of Borena at Yabelo General Hospital.

Method: The study design was a retrospective cohort study, with a sample size of 293 individuals living with HIV/AIDS, based on recorded data. This research utilized survival model analysis, employing Kaplan-Meier plots, the log-rank test, and Cox proportional hazard model analysis.

Result: Out of the total sample size, 179 (61.1%) were female and 114 (38.1%) were male. Among these males, 36 (31.6%) were deceased. The analysis using the Cox proportional hazard model revealed that the following variables were significantly associated with the survival time of HIV/AIDS patients: gender, educational status, area of residence, tuberculosis (TB), and opportunistic infections.

Conclusions: We concluded that individuals living with HIV/AIDS in urban areas have a lower risk of death compared to those in rural areas, indicating that rural residents have a reduced survival probability. Therefore, the Borena zone administration should focus on adult patients to enhance life expectancy.

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来源期刊
AIDS Research and Therapy
AIDS Research and Therapy INFECTIOUS DISEASES-
CiteScore
3.80
自引率
4.50%
发文量
51
审稿时长
16 weeks
期刊介绍: AIDS Research and Therapy publishes articles on basic science, translational, clinical, social, epidemiological, behavioral and educational sciences articles focused on the treatment and prevention of HIV/AIDS, and the search for the cure. The Journal publishes articles on novel and developing treatment strategies for AIDS as well as on the outcomes of established treatment strategies. Original research articles on animal models that form an essential part of the AIDS treatment research are also considered
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