纺锤形细胞脂肪瘤,一种罕见的良性脂肪细胞肿瘤:病例报告

Nitin Sajankila , Amanda Graveson , Veronica Ulici , John DiFiore
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引用次数: 0

摘要

导言纺锤形细胞脂肪瘤是一种罕见的良性软组织肿块,易于手术切除治疗。虽然纺锤形细胞脂肪瘤通常发生在男性身上,而且发病年龄较晚,但在本病例报告中,我们介绍了一例发生在女性青少年身上的纺锤形细胞脂肪瘤。病例介绍 患者是一名健康的 16 岁女性,体检时发现其后侧有一个柔软、可移动、界限不清的肿块。由于超声检查显示不清,患者接受了磁共振成像(MRI)检查,结果显示皮下组织中有一个界限清楚、T1 和 T2 明亮的卵圆形病灶。核磁共振成像显示,肿块大小为 7.4 x 4 x 4.5 厘米,符合良性脂肪肿块的特征。该肿块被认为是脂肪瘤,建议将其切除以确诊。然而,由于担心接受手术,患者选择了推迟。两年后,她再次就诊,发现同一部位有一个更大的肿块,于是进行了手术切除。切除时,肿块看起来光滑、闪亮、脂肪较多,大小为 13.5 x 9.8 x 4.5 厘米。组织学检查显示,包裹的纤维脂肪组织含有脂肪细胞和 CD34 染色的纺锤形细胞,与纺锤形细胞脂肪瘤的诊断一致。结论纺锤形细胞脂肪瘤无法在术前与脂肪瘤区分开来。
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Spindle cell lipoma, a rare and benign adipocytic tumor: A case report

Introduction

Spindle cell lipomas are a rare, benign soft tissue mass that are easily treated with surgical excision. Although typically occurring in males and much later in life, in this case report, we present a case of a spindle cell lipoma occurring in a female teenager.

Case presentation

The patient is a healthy 16-year-old Female who presented with a soft, mobile, and poorly defined posterior flank mass on physical exam. As it was not well-visualized by ultrasound, a magnetic resonance image (MRI) was obtained, revealing a well-defined, T1 and T2 bright, ovoid lesion in the subcutaneous tissue. On MRI, the mass measured 7.4 x 4 × 4.5 cm and was consistent with a benign fatty mass. The mass was thought to be a lipoma and it was recommended that it be excised to confirm the diagnosis. However, the patient elected to defer due to concerns about undergoing surgery. Two years later she re-presented with a much larger mass in the same region and a surgical excision was then performed. On excision, the mass appeared smooth, glistening, and fatty, measuring 13.5 x 9.8 × 4.5 cm. Histology revealed encapsulated fibroadipose tissue containing both adipocytes and CD34-staining spindle cells, consistent with a diagnosis of spindle cell lipoma. The patient continues to do well 6 months later with no evidence of recurrence.

Conclusion

Spindle cell lipoma cannot be differentiated from lipomas pre-operatively.

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来源期刊
CiteScore
0.60
自引率
25.00%
发文量
348
审稿时长
15 days
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