利桑珠单抗治疗小袋克罗恩病的有效性和安全性。

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY ACG Case Reports Journal Pub Date : 2024-08-29 eCollection Date: 2024-09-01 DOI:10.14309/crj.0000000000001476

Nan Lan, Bo Shen

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引用次数: 0

摘要

利桑珠单抗在治疗中重度克罗恩病（CD）方面已显示出疗效。利妥昔单抗用于治疗克罗恩病（CD）小袋，此前尚未见报道。在这里，我们用利桑珠单抗治疗了 10 例暴露于生物制剂的小袋 CD 患者。一些患者的炎症在内镜下有所改善，但临床改善甚微。我们的研究结果值得进一步研究，以验证利坦珠单抗治疗胃袋 CD 的有效性和安全性。

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Efficacy and Safety of Risankizumab in the Treatment of Crohn's Disease of the Pouch.

Risankizumab has shown efficacy in the treatment of moderate-to-severe Crohn's disease (CD). The use of risankizumab in the treatment of CD of the pouch has not been previously reported. Here, we have 10 patients with biologics exposed CD of the pouch treated with risankizumab. Some patients showed endoscopic improvement regarding inflammation with minimal clinical improvement. Our findings warrant further study to validate the efficacy and safety of risankizumab in the treatment of CD of the pouch.

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.