一名克罗恩病患者的多灶性爱泼斯坦-巴氏病毒阳性皮肤黏膜溃疡

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY ACG Case Reports Journal Pub Date : 2024-08-29 eCollection Date: 2024-09-01 DOI:10.14309/crj.0000000000001468

Lotus Alphonsus, Qi Zhang, Vipul Jairath

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引用次数: 0

摘要

爱泼斯坦-巴氏病毒阳性皮肤黏膜溃疡（EBVMCU）是一种罕见的成熟 B 细胞肿瘤新类型，通常与免疫抑制有关。其病程通常为良性，在停用或减少免疫抑制剂剂量后可自然消退。我们报告了一例因直肠乙状结肠克罗恩病而长期服用硫唑嘌呤治疗的 48 岁女性病例。与通常与 EBVMCU 相关的流行部位（如口腔粘膜和皮肤）不同，该患者的发病部位位于胃肠道和上颈部。这些部位的组织病理学检测结果呈阳性，与 EBVMCU 一致，由于肠穿孔和对恶性肿瘤的担忧，患者接受了切除手术。

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Multifocal Epstein-Barr Virus-Positive Mucocutaneous Ulcers in a Patient With Crohn's Disease.

Epstein-Barr Virus-positive mucocutaneous ulcer (EBVMCU) is a rare and new category of mature B-cell neoplasms commonly linked to immunosuppression. It often has a benign course and regresses spontaneously after discontinuation or dose reduction of immunosuppressive agents. We report the case of a 48-year-old woman on long-term azathioprine therapy for rectosigmoid Crohn's disease. In contrast to the prevalent sites typically associated with EBVMCU, such as the oral mucosa and skin, this patient was found to have locations in the gastrointestinal tract and upper neck. These areas tested positive for histopathology consistent with EBVMCU and were excised due to bowel perforation and concern for malignancy.

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.